Outeiro, Tiago Fleming

Authors Swaih AM, Breda C, Sathyasaikumar KV, Allcock N, Collier MEW, Mason RP, Feasby A, Herrera F, Outeiro TF, Schwarcz R, Repici M, Giorgini F Journal Biomedicines Citation Biomedicines 2022, 10(9), 2294. Abstract The flavoprotein kynurenine 3-monooxygenase (KMO) is localised to the outer mitochondrial membrane and catalyses the synthesis of

Authors Brás IC, Khani MH, Riedel D, Parfentev I, Gerhardt E, van Riesen C, Urlaub H, Gollisch T, Outeiro TF Journal Journal of Proteomics Citation J Proteomics. 2022 Sep 8:104721. Abstract Extracellular vesicles (EVs) are important mediators in intercellular communication. However, understanding the biological origin and functional effects of EVs

Authors Santos CC, Cardim-Pires TR, Shvachiy L, Fonseca-Fonseca LA, Muñoz P, Almeida ÁMAN, Costa ACS, Teles-Souza J, Ochoa-Rodríguez E, de Fátima Dias Costa M, Palhano FL, Segura-Aguilar J, Barbosa DB, do Bomfim MR, Dos Santos Junior MC, Leite FHA, da Rocha Pita SS, Costa SL, Núñez-Figueredo Y, Outeiro TF, Foguel

Authors Shvachiy L, Amaro-Leal Â, Outeiro TF, Rocha I, Geraldes V Journal Biology Citation Biology (Basel). 2022 Aug 3;11(8):1164. Abstract Lead is a heavy metal whose widespread use has resulted in environmental contamination and significant health problems, particularly if the exposure occurs during developmental stages. It is a cumulative toxicant

Authors Koss DJ, Erskine D, Porter A, Palmoski P, Menon H, Todd OGJ, Leite M, Attems J, Outeiro TF Journal Acta Neuropathologica Communications Citation Acta Neuropathol Commun. 2022 Jul 6;10(1):98. Abstract Dementia with Lewy bodies (DLB) is pathologically defined by the cytoplasmic accumulation of alpha-synuclein (aSyn) within neurons in the

Authors Buratti FA, Boeffinger N, Garro HA, Flores JS, Hita FJ, Gonçalves PDC, Copello FDR, Lizarraga L, Rossetti G, Carloni P, Zweckstetter M, Outeiro TF, Eimer S, Griesinger C, Fernández CO Journal Protein Science Citation Protein Sci. 2022 Jul;31(7):e4360. Abstract Recent studies revealed that molecular events related with the physiology

Authors Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF Journal Neurobiology of Disease Citation Neurobiol Dis. 2022 Jun 15;168:105696. Abstract Synucleinopathies are a group of progressive neurodegenerative diseases known for the accumulation of insoluble aggregates containing the protein alpha-synuclein (aSyn). Recently, it has been assumed

Authors Schaffner SL, Wassouf Z, Lazaro DF, Xylaki M, Gladish N, Lin DTS, MacIsaac J, Ramadori K, Hentrich T, Schulze-Hentrich JM, Outeiro TF, Kobor MS Journal Human Molecular Genetics Citation Hum Mol Genet. 2022 May 14:ddac104. Abstract Parkinson’s disease (PD) is a neurological disorder with complex interindividual etiology that is

Authors Chegão A, Guarda M, Alexandre BM, Shvachiy L, Temido-Ferreira M, Marques-Morgado I, Fernandes Gomes B, Matthiesen R, Lopes LV, Florindo PR, Gomes RA, Gomes-Alves P, Coelho JE, Outeiro TF, Vicente Miranda H Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2022 Apr 25;8(1):51. Abstract Alpha-synuclein (aSyn) is a central

Authors Ding Y, Korchak S, Mamone S, Jagtap AP, Stevanato G, Sternkopf S, Moll D, Schroeder H, Becker S, Fischer A, Gerhardt E, Outeiro TF, Opazo F, Griesinger C, Glöggler S Journal Chemistry Methods Citation Chem. Methods 2022, e202200023. Abstract Nuclear magnetic resonance (NMR) is widely applied from analytics to