Fischer, André

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31.03.2025

Disease Severity Across Psychiatric Disorders Is Linked to Pro-Inflammatory Cytokines

Authors Solomon PAJ, Budde M, Kohshour MO, Adorjan K, Heilbronner M, Navarro-Flores A, Papiol S, Reich-Erkelenz D, Schulte EC, Senner F, Vogl T, Kaurani L, Krugger DM, Sananbenesi F, Pena T, Burkhardt S, Schutz AL, Anghelescu IG, Arolt V, Baune BT, Dannlowski U, Dietrich DE, Fallgatter AJ, Figge C, Juckel
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29.01.2025

Engineered heart muscle allografts for heart repair in primates and humans

Authors Jebran AF, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, Ensminger S, Bremmer F, Moussavi A, Yang H, Qin X, Mißbach S, Drummer C, Baraki H, Boretius S, Hasenauer C, Nette T, Kowallick J, Ritter CO, Lotz J, Didié M, Mietsch M, Meyer T, Kensah G, Krüger
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09.01.2025

LncRNA 3222401L13Rik Is Upregulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3

Authors Schröder S, Sakib MS, Krüger DM, Pena T, Burkhardt S, Schütz AL, Sananbenesi F, Fischer A Journal Noncoding RNA Citation Noncoding RNA. 2025 Jan 9;11(1):2. Abstract Aging leads to cognitive decline and increased risk of neurodegenerative diseases. While molecular changes in central nervous system (CNS) cells contribute to this
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25.12.2024

Cognitive decline and neuroinflammation in a mouse model of obesity: An accelerating role of ageing

Authors Rajput M, Malik IA, Methi A, Cortés Silva JA, Fey D, Wirths O, Fischer A, Wilting J, von Arnim CAF Journal Brain, Behavior, and Immunity Citation Brain Behav Immun. 2024 Dec 25:S0889-1591(24)00883-3. Abstract Obesity, a pandemic, worldwide afflicts almost one billion people. Obesity and ageing share several pathological pathways
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30.10.2024

Stress Vulnerability Exposed by Mapping Brain Network States to Single-Cell Transcriptomes

Authors Fischer A, Radulovic J Journal Biological Psychiatry Citation Biol Psychiatry. 2024 Dec 1;96(11):832-834. Abstract No abstract available. DOI 10.1016/j.biopsych.2024.08.024   Pubmed Link
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05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
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18.09.2024

The plasma miRNAome in ADNI: signatures to aid the detection of at-risk individuals

Authors Krüger MD, Pena-Centeno T, Lui S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher S, Burkhardt S, Schütz AL, Wang Y, Shaw LM, Brodsky A, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A Journal
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18.09.2024

Plasma miRNAs across the Alzheimer’s disease continuum: Relationship to central biomarkers

Authors Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K; Alzheimer’s Disease Neuroimaging Initiative Journal
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12.09.2024

The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy

Authors Chopra A, Xylaki M, Yin F, Castro-Hernández R, Merghani M, Grande V, Mollenhauer B, Fischer A, Outeiro TF Journal BioRxiv Citation bioRxiv 2024.09.12.612649. Abstract N6-methyladenosine (m6A) is the most abundant and conserved transcriptional modification in eukaryotic RNA, regulating RNA fate. While the functions of m6A in the development of
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29.08.2024

Blood-derived microRNAs are related to cognitive domains in the general population

Authors Melas K, Talevi V, Imtiaz MA, Etteldorf R, Estrada S, Krüger DM, Pena-Centeno T, Aziz NA, Fischer A, Breteler MMB Journal Alzheimer’s & Dementia Citation Alzheimers Dement. 2024 Aug 29. Abstract Introduction: Blood-derived microRNAs (miRNAs) are potential candidates for detecting and preventing subclinical cognitive dysfunction. However, replication of previous
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