Fischer, André

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13.01.2024

A single-cell transcriptomic analysis of the mouse hippocampus after voluntary exercise

Authors Methi A, Islam MR, Kaurani L, Sakib MS, Krueger DM, Pena T, Burkhardt S, Liebetanz D, Fischer A Journal Molecular Neurobiology Citation Mol Neurobiol. 2024 Jan 13. Abstract Exercise has been recognized as a beneficial factor for cognitive health, particularly in relation to the hippocampus, a vital brain region
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13.11.2023

Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency

Authors Schlotawa l, Matysiak K, Kettwig M, Ahrens-Nicklas RC, Baud M, Berulava T, Brunetti-Pierri N, Gagne A, Herbst ZM, Maguire JA, Monfregola J, Pena T, Radhakrishnan K, Schröder S, Waxman EA, Ballabio A, Dierks T, Fischer A, French DL, Gelb MH, Gärtner J Journal Neuropediatrics Citation Neuropediatrics 2023; 54(S 01):
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13.09.2023

Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression

Authors Kaurani L, Besse M, Methfessel I, Methi A, Zhou J, Pradhan R, Burkhardt S, Kranaster L, Sartorius A, Habel U, Grözinger M, Fischer A, Wiltfang J, Zilles-Wegner D Journal Translational Psychiatry Citation Transl Psychiatry. 2023 Sep 13;13(1):294. Abstract There is a strong medical need to develop suitable biomarkers to
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19.08.2023

Bioengineering of a human innervated cardiac muscle model

Authors Schneider LV, Bao G, Methi A, Jensen O, Schmoll KA, Setya MG, Sakib MS, Fahud AL, Brockmoeller J, Fischer A, Liaw NY, Zimmermann WH, Zafeiriou MP Journal BioRxiv Citation bioRxiv 2023.08.18.552653. Abstract Cardiac autonomic neurons control cardiac contractility. Dysregulation of the autonomic nervous system can lead to sympathetic overdrive
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21.03.2023

A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia

Authors Kaurani L, Islam MR, Heilbronner U, Krüger DM, Zhou J, Methi A, Strauss J, Pradhan R, Burkhardt S, Pena T, Erlebach L, Bühler A, Budde M, Senner F, Oraki Kohshour M, Schulte EC, Schmauß M, Reininghaus EZ, Juckel G, Kronenberg-Versteeg D, Delalle I, Odoardi F, Flügel A, Schulze TG,
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22.02.2023

Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts

Authors Castro-Hernández R, Berulava T, Metelova M, Epple R, Peña Centeno T, Sakib MS, Burkhart S, Ninov M, Bohnsack KE, Bohnsack MT, Delalle I, Fischer A Journal Proceedings of the National Academy of Sciences Citation Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2204933120. Abstract N6-methyladenosine (m6A) regulates mRNA
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15.02.2023

Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency

Authors Schlotawa L, Tyka K, Kettwig M, Ahrens-Nicklas RC, Baud M, Berulava T, Brunetti-Pierri N, Gagne A, Herbst ZM, Maguire JA, Monfregula J, Pena T, Radhakrishnan K, Schröder S, Waxman EA, Ballabio A, Dierks T, Fischer A, French DL, Gelb MH, Gärtner J   Journal EMBO Molecular Medicine   Citation
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11.02.2023

Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls

Authors Senner F, Schneider-Axmann T, Kaurani L, Zimmermann J, Wiltfang J, von Hagen M, Vogl T, Spitzer C, Senner S, Schulte EC, Schmauß M, Schaupp SK, Reimer J, Reich-Erkelenz D, Papiol S, Kohshour MO, Lang FU, Konrad C, Kirchner SK, Kalman JL, Juckel G, Heilbronner M, Heilbronner U, Figge C,
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08.02.2023

NFATc1 is a central mediator of EGFR-induced ARID1A chromatin dissociation during acinar cell reprogramming

Authors Zhang Z, Wang X, Hamdan FH, Likhobabina A, Patil S, Aperdannier L, Sen M, Traub J, Neesse A, Fischer A, Papantonis A, Singh SK, Ellenrieder V, Johnsen SA, Hessmann E Journal Cellular and Molecular Gastroenterology and hepatology Citation Cell Mol Gastroenterol Hepatol. 2023 Feb 7:S2352-345X(23)00018-8. Abstract Background & aims:
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06.02.2023

Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF

Authors Antoniou A, Auderset L, Kaurani L, Sebastian E, Zeng Y, Allahham M, Cases-Cunillera S, Schoch S, Gruendemann J, Fischer A, Schneider A   Journal Cell Reports   Citation Cell Rep. 2023 Feb 6;42(2):112063.   Abstract Extracellular vesicles (EVs) have emerged as mediators of cellular communication, in part via the
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