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Generation of human brain organoids with the ability to learn
28.08.2020

Generation of human brain organoids with the ability to learn

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering
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New insights into lung tissue in Covid-19 disease
21.08.2020

New insights into lung tissue in Covid-19 disease

Researchers led by Göttingen University develop new three-dimensional imaging technique to visualize tissue damage in severe Covid-19 (pug) Physicists at the University of Göttingen and the Cluster of Excellence “Multiscale Bioimaging” (MBExC), together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique
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CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects
05.08.2020

CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for the Noonan Syndrome. Publication in the renowned journal “Circulation“. (umg/ mbexc) Congenital heart diseases are the most common organ defects. They occur
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In one sweep: Visualization of protein mobility in the synapse
30.07.2020

In one sweep: Visualization of protein mobility in the synapse

(mbexc/umg) All functions of the neural system, including body movements, sensory reactions, and information processing in the brain, depend on the constant and controlled communication between nerve cells. The contact sites between nerve cells, the synapses, have been extensively studied over the last decades, extending our understanding of brain functioning
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On the way to the optical cochlear implant
22.07.2020

On the way to the optical cochlear implant

Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear implants based on light-emitting diodes. Published in Science Translational Medicine. (mbexc/umg) The cochlear implant (CI) enables worldwide over 700,000 people with profoundly
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New biosensor detects cell-to-cell transmission of the Parkinson-associated protein α-Synuclein
17.07.2020

New biosensor detects cell-to-cell transmission of the Parkinson-associated protein α-Synuclein

Scientists of the Cluster of Excellence Multiscale Bioimaging develop a new biosensor capable of detecting the transmission of human α-synuclein, a key protein associated to Parkinson’s disease. Published in Nature Communications. (umg/mbexc) Human alpha-synuclein (hαSyn) is a physiological protein that is primarily found in nerve cells, and is involved in
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Lighting array in the ear: First use of multi-channel cochlear implants with microscale light-emitting diodes
06.07.2020

Lighting array in the ear: First use of multi-channel cochlear implants with microscale light-emitting diodes

A milestone in hearing research: Researchers at the University Medical Center Göttingen and the University of Freiburg combine for the first time gene therapy in the cochlea with optical cochlear implants to optogenetically activate the auditory pathway in gerbils. Published in EMBO Molecular Medicine. (umg/mbexc) Conventional hearing prostheses, so-called cochlear
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Coupled hair cells in the inner ear – „Together we are strong!“
25.06.2020

Coupled hair cells in the inner ear – „Together we are strong!“

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For the first time, scientists of the Göttingen Campus, the Cluster of Excellence “Multiscale Bioimaging” and the University College London have
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