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Egg cell maintenance: Long-lived proteins may be essential
10.07.2024

Egg cell maintenance: Long-lived proteins may be essential

Female mammals – including humans – are born with all of their egg cells. Of a woman’s one to two million egg cells, about 400 mature before menopause and can be fertilized. Some egg cells therefore survive for several decades – and need to remain functional over this long time.
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Minister of Science Falko Mohrs visits Göttingen Cluster of Excellence
22.03.2024

Minister of Science Falko Mohrs visits Göttingen Cluster of Excellence

Falko Mohrs, Minister of Science and Culture of Lower Saxony, visited the researchers of the Göttingen Cluster of Excellence “Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells” (MBExC) on Friday, 22 March 2024. The occasion was the continuation application to be submitted by MBExC in August to apply
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Heart & Brain – Understanding Together
13.03.2024

Heart & Brain – Understanding Together

New special exhibition at the Forum Wissen opens on 18 April 2024   How does a “patch” for the heart work? Can we hear with light? And how can insights from basic research be used to help diagnose and treat diseases? The “Heart & Brain – understanding together” exhibition examines
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Else Kröner Fresenius Center for Optogenetic Therapies approved
08.03.2024

Else Kröner Fresenius Center for Optogenetic Therapies approved

Else Kröner-Fresenius-Stiftung (EKFS) supports new research center for optogenetic therapies with 37.4 million euros over ten years at the University Medical Center Göttingen (UMG). The state of Lower Saxony is strongly supporting the establishment of the center and, together with the UMG, is holding out the prospect of up to
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Light into the darkness of photosynthesis: 3D insights into the copying machine of chloroplasts
01.03.2024

Light into the darkness of photosynthesis: 3D insights into the copying machine of chloroplasts

• A molecular 3D snapshot of the copying machine in chloroplasts, the RNA polymerase PEP, provides new insights into the evolution and function of plant photosynthesis. • Using a cryo-electron microscope, a high-resolution image of a 19-subunit PEP complex from white mustard (Sinapis alba) was taken. • Evolutionary analyses indicate
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New gene therapy for children born deaf in clinical trials
01.02.2024

New gene therapy for children born deaf in clinical trials

To date, hearing impairment can only be treated with medical devices such as hearing aids or cochlear implants. Gene therapy could offer an alternative in certain cases in the future. Building on pioneering work by researchers at the University Medical Center Göttingen (UMG), children suffering from a hearing impairment due
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Energy supply in human cells is subject to quality control
19.01.2024

Energy supply in human cells is subject to quality control

Researchers at the University Medical Center Göttingen (UMG) and members of the MBExC have discovered a new quality control mechanism that regulates the energy production in human cells. This process takes place in mitochondria, the power plants of the cell. Malfunctions of mitochondria lead to serious diseases of the nerves,
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New insights into sound coding in our ears
14.12.2023

New insights into sound coding in our ears

Sensory cells and neurons in the ear communicate by secreting neurotransmitter in response to sound stimuli. Scientists of the University Medical Center Göttingen, the Cluster of Excellence Multiscale Bioimaging, and the Max Planck Institute for Multidisciplinary Sciences describe new details of this process that regulates the release of neurotransmitters and
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Detecting side effects of new drugs on the heart more efficiently
05.12.2023

Detecting side effects of new drugs on the heart more efficiently

Scientists at the University Medical Center and the University of Göttingen have developed a new approach to keep intact heart tissue for about two weeks in culture for more efficient cardiotoxicity screening of new active substances and therapeutic approaches. The advantage: this method is already effective in a very early
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Protein stock for the beginning of a new life
06.11.2023

Protein stock for the beginning of a new life

How mysterious structures in the egg cell supply the early embryo as protein storage sites When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs to
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