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Prof. Dr. Claus Ropers / Foto: spförtner

27.04.2022

ERC Advanced Grant for MBExC member Claus Ropers

MBExC member Claus Ropers, professor at the Physics department at Göttingen University and director of the Department of Ultrafast Dynamics at the Max Planck Institute for Multidisciplinary Sciences, receives the prestigious Advanced Grant from the European Commission for his innovative research project. With the ERC funding, Ropers’ team wants to
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Prof. Dr. med. Tobias Moser, Director of the Institute for Auditory Neuroscience Göttingen, UMG. Photo: MBExC / spförtner

26.04.2022

European funding for excellent research on hearing

Auditory neuroscientist of the University Medical Center Göttingen receives Advanced Grant of the European Research Council for the second time. Tobias Moser, MD, Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen (UMG) was awarded an Advanced Grant of the European Research Council (ERC). The ERC
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Prof. Dr. med. Tobias Moser, Director of the Institute for Auditory Neuroscience Göttingen, UMG. Photo: MBExC / spförtner

26.04.2022

European funding for excellent research on hearing

MBExC speaker Tobias Moser, director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen, received an ERC Advanced Grant. The European Research Council (ERC) supports his research project „Solving the dynamic range problem of hearing: deciphering and harnessing cochlear mechanisms of sound intensity coding (DynaHear)“ over five
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25.04.2022

Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes

Authors Chegão A, Guarda M, Alexandre BM, Shvachiy L, Temido-Ferreira M, Marques-Morgado I, Fernandes Gomes B, Matthiesen R, Lopes LV, Florindo PR, Gomes RA, Gomes-Alves P, Coelho JE, Outeiro TF, Vicente Miranda H Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2022 Apr 25;8(1):51. Abstract Alpha-synuclein (aSyn) is a central
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21.04.2022

A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry

Authors Li F, Fornasiero EF, Dankovich TM, Kluever V, Rizzoli SO Journal International Journal of Molecular Sciences Citation Int. J. Mol. Sci. 2022, 23, 4615. Abstract Nano secondary ion mass spectrometry (nanoSIMS) imaging is a rapidly growing field in biological sciences, which enables investigators to describe the chemical composition of
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21.04.2022

Background calcium influx in arrhythmia: lead actor or extra?

Authors Fakuade FE, Fauconnier J, Voigt N. Journal Journal of Physiology Citation J Physiol. 2022 Apr 21. Abstract No abstract available DOI 10.1113/JP283032 Pubmed Link  
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19.04.2022

Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

Authors Riemenschneider H, Guo Q, Bader J, Frottin F, Farny D, Kleinberger G, Haass C, Mann M, Hartl FU, Baumeister W, Hipp MS, Meissner F, Fernández-Busnadiego R, Edbauer D Journal EMBO Reports Citation EMBO Rep. 2022 Apr 19:e53890. Abstract Aggregation of the multifunctional RNA-binding protein TDP-43 defines large subgroups of
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15.04.2022

Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration

Authors Luebben AV, Bender D, Becker S, Crowther LM, Erven I, Hofmann K, Söding J, Klemp H, Bellotti C, Stäuble A, Qiu T, Kathayat RS, Dickinson BC, Gärtner J, Sheldrick GM, Krätzner R, Steinfeld R Journal Science Advances Citation Sci Adv. 2022 Apr 15;8(15):eabj8633. Abstract Genetic CLN5 variants are associated
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Indicated are the intracellular steps of the Gq signaling cascade, which can now be controlled by scientists using light to drive activity in transgenic mouse hearts (left) and contractions in the small intestine (right). Source: Prof. Brügmann / umg.

14.04.2022

A new tool for optogenetics: human receptor for studying cell function with light

Scientists of the University Medical Center Göttingen identify the human OPN5 receptor as a new target to activate cells and to study the principles of how cells communicate with each other. Published on 1 April 2022 in the renowned journal Nature Communications. Link to the MBExC press release
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Indicated are the intracellular steps of the Gq signaling cascade, which can now be controlled by scientists using light to drive activity in transgenic mouse hearts (left) and contractions in the small intestine (right). Source: Prof. Brügmann / umg.

14.04.2022

A new tool for optogenetics: human receptor for studying cell function with light

Scientists of the University Medical Center Göttingen identify the human OPN5 receptor as a new target to activate cells and to study the principles of how cells communicate with each other. Published on 1 April 2022 in the renowned journal Nature Communications. Gq proteins and the signaling cascade they trigger
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