Susann Meyer – Page 185

29.06.2020

μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve

Dieter A, Klein E, Keppeler D, Jablonski L, Harczos T, Hoch G, Rankovic V, Paul O, Jeschke M, Ruther P, Moser T

26.06.2020

Figure: Coupled hair cells (left): Fluorescence microscopy image of a cell cluster of five coupled inner hair cells (pear-shaped with bright spots).
The second cell from the left was loaded with a fluorescent dye that labels the synaptic ribbon using the patch-clamp technique. From there, the dye spreads into the neighbouring hair cells and marks the synaptic ribbons (bright spots). Source: Institute for Auditory Neuroscience / UMG.
A “mini-syncytium” of three coupled inner hair cells (right); the connection is simplified as a tube formed by fused cell membranes: The electrical signals are transmitted via coupling of the cells. This mechanism reduces the stochastic noise of signal transmission at the ribbon synapses with the neurons forming the auditory nerve. From there the information is transmitted to a common target neuron in the brain, further reducing the noise and resulting in higher hearing sensitivity.
Source: Jean et al., Nat Commun, 2020; Suppl. Part.

26.06.2020

Coupled hair cells in the inner ear – „Together we are strong!“

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For […]

25.06.2020

Macromolecular and electrical coupling between inner hair cells in the rodent cochlea

Jean P, Anttonen T, Michanski S, de Diego AMG, Steyer AM, Neef A, Oestreicher D, Kroll J, Nardis C, Pangršič T, Möbius W, Ashmore J, Wichmann C, Moser T

25.06.2020

Figure: Coupled hair cells (left): Fluorescence microscopy image of a cell cluster of five coupled inner hair cells (pear-shaped with bright spots).
The second cell from the left was loaded with a fluorescent dye that labels the synaptic ribbon using the patch-clamp technique. From there, the dye spreads into the neighbouring hair cells and marks the synaptic ribbons (bright spots). Source: Institute for Auditory Neuroscience / UMG.
A “mini-syncytium” of three coupled inner hair cells (right); the connection is simplified as a tube formed by fused cell membranes: The electrical signals are transmitted via coupling of the cells. This mechanism reduces the stochastic noise of signal transmission at the ribbon synapses with the neurons forming the auditory nerve. From there the information is transmitted to a common target neuron in the brain, further reducing the noise and resulting in higher hearing sensitivity.
Source: Jean et al., Nat Commun, 2020; Suppl. Part.

25.06.2020

Coupled hair cells in the inner ear – „Together we are strong!“

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For […]

22.06.2020

Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis

Backhaus SJ, Lange T, Beuthner BE, Topci R, Wang X, Kowallick JT, Lotz J, Seidler T, Toischer K, Zeisberg EM, Puls M, Jacobshagen C, Uecker M, Hasenfuß G, Schuster A

16.06.2020

Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations

Farnung L, Ochmann M, Cramer P