Generation of human brain organoids with the ability to learn

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering of human organoids to for the first time bioengineer the human brain at the macroscale level with comprehensive network function. The so called Bioengineered Neuronal Organoids (BENOs) recapitulate important morphological features of the human brain and functions underlying memory and learning. The study has been published in Nature Communications.

Link to the press release