Enderlein, Jörg

Authors Habenstein F, Jensen N, Stumpf D, Chizhik AI, Leutenegger M, Chang J, Fognini A, Qin-Dregely J, Zadeh IE, Kirck LL, Enderlein J, Inamdar K, Hell SW, Jakobs S Journal Proceedings of the National Academy of Sciences of the USA Citation Proc Natl Acad Sci U S A. 2026 Sep;123(35):e2533451123.

Authors Marx D, Malsbenden D, Gligonov I, Wöll D, Enderlein J, Nevskyi O Journal ChemRxiv Citation ChemRxiv. 18 August 2026. Abstract Fluorescence lifetimes near dielectric interfaces depend on molecular dipole orientation, but this relationship becomes more complex when emitters are confined within finite nanoscopic films. Here, we combine radially polarized

Authors Gallea JI, Karedla N, Wang D, Zhao B, Chen L, Enderlein J, Chen T Journal Science Advances Citation Sci Adv. 2026 May 15;12(20):eaed9613. Abstract The dynamic behavior of cellular membranes underpins essential biological processes, including signal transduction, intracellular trafficking, and mechanotransduction. However, simultaneously quantifying lateral molecular diffusion and vertical

Authors Gligonov I, Loetgering L, Tenopala-Carmona F, Hsieh CL, Gregor I, Enderlein J Journal BioRxiv Citation bioRxiv 2026.04.28.721333 Abstract Optical microscopy is fundamental to modern life-science research, yet interpreting its results requires precise modelling of point spread functions (PSFs) within complex environments. This manuscript introduces a versatile and efficient approach

Authors Albert L, Basak S, Koerner H, Oleksiievets N, Mougios N, Cotroneo ER, Frei MS, Enderlein J, Broichhagen J, Simeth NA, Tsukanov R, Opazo F Journal BioRxiv Citation bioRxiv 2026.03.02.709025. Abstract Multiplexed fluorescence imaging is limited by spectral overlap, whereas fluorescence lifetime provides an orthogonal encoding dimension. We replace genetically

Authors Marx D, Gligonov I, Malsbenden D, Wöll D, Nevskyi O, Enderlein J. Journal Nano Letters Citation Nano Lett. 2026 Jan 20. Abstract Single fluorescent molecules, acting as ideal point dipoles, offer a unique means to probe light-matter interactions at the nanoscale. Here, we exploit this property to map the

Authors Basak S, Vu KC, Mougios N, Oleksiievets N, Pollack YG, Brandenburg S, Opazo F, Lehnart SE, Enderlein J, Tsukanov R Journal ACS Nano Citation ACS Nano. 2026 Jan 1. Abstract DNA-based Point Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) is a powerful variant of single-molecule localization microscopy (SMLM) that

Authors Basak S, Inamdar K, Pollack YG, Albert L, Jans DC, Jakobs S, Enderlein J, Tsukanov R, Opazo F Journal BioRxiv Citation bioRxiv 2025.12.17.694880 Abstract Direct STORM relies on robust fluorophore blinking; observations suggest that AlexaFluor647 underperforms when coupled to nanobodies, thereby undermining the advantages of nanobodies. We show that

Authors Enderlein J Journal eLight Citation eLight 5, 34 (2025). Abstract Historically constrained by the low throughput of traditional Time-Correlated Single-Photon Counting (TCSPC), a new method utilizes an optimized, time-gated single-photon camera acquisition scheme for achieving single-molecule lifetime precision comparable to TCSPC, but across a wide field of view simultaneously.

Authors Stumpf D, Jensen N, Mittelheisser C, Keller-Findeisen J, Chizhik AI, Kamper M, Diekmann T, Habenstein F, Jansen I, Enderlein J, Sliwa M, Inamdar K, Hell SW, Jakobs S Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S