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28.03.2022

Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system

Authors Calapai A, Cabrera-Moreno J, Moser T, Jeschke M Journal Nature Communications Citation Nat Commun. 2022 Mar 28;13(1):1648. Abstract Devising new and more efficient protocols to analyze the phenotypes of non-human primates, as well as their complex nervous systems, is rapidly becoming of paramount importance. This is because with genome-editing
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12.03.2022

Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene

Authors Pater JA, Penney C, O’Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble
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11.03.2022

Methods for multiscale structural and functional analysis of the mammalian cochlea

Authors Vogl C, Neef J, Wichmann C Journal Molecular and Cellular Neuroscience Citation Mol Cell Neurosci. 2022 Mar 11;120:103720. Abstract The mammalian cochlea is a snail-shaped structure deeply that is embedded in the temporal bone and harbors the auditory sensory epithelium – the organ of Corti. Since the discovery of
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10.03.2022

A mathematical model for electrical activity in pig atrial tissue

Authors Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Journal Frontiers in Physiology Citation Front Physiol. 2022 Mar 10;13:812535. Abstract State of the art mathematical models are currently used to bridge the gap between basic research conducted in the laboratory and preclinical research conducted on large
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09.03.2022

Modeling charge separation in charged nanochannels for single-molecule electrometry

Authors Enderlein J, Sakhapov D, Gregor I, Croci M, Karedia N Journal The Journal of Chemical Physics Citation J. Chem. Phys. 156, 105104 (2022) Abstract We model the transport of electrically charged solute molecules by a laminar flow within a nanoslit microfluidic channel with electrostatic surface potential. We derive the governing
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08.03.2022

Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration

Authors Liu JK, Karamanlis D, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2022 Mar 8;18(3):e1009925. Abstract A central goal in sensory neuroscience is to understand the neuronal signal processing involved in the encoding of natural stimuli. A critical step towards this goal is the development of successful
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08.03.2022

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

Authors Haupt LP, Rebs S, Maurer W, Hübscher D, Tiburcy M, Pabel S, Maus A, Köhne S, Tappu R, Haas J, Li Y, Sasse A, Santos CCX, Dressel R, Wojnowski L, Bunt G, Möbius W, Shah AM, Meder B, Wollnik B, Sossalla S, Hasenfuss G, Streckfuss-Bömeke K Journal Basic Research
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08.03.2022

The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic

Authors Dankovich TM, Rizzoli SO Journal Frontiers in Synaptic Neuroscience Citation Front Synaptic Neurosci. 2022 Mar 8;14:854956. Abstract In the adult brain, synapses are tightly enwrapped by lattices of the extracellular matrix that consist of extremely long-lived molecules. These lattices are deemed to stabilize synapses, restrict the reorganization of their
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07.03.2022

Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice

Authors Svetlove A, Albers J, Hülsmann S, Markus MA, Zschüntzsch J, Alves F, Dullin C Journal Cells Citation Cells. 2022 Mar 7;11(5):918. Abstract Duchenne muscular dystrophy (DMD) is the most common x-chromosomal inherited dystrophinopathy which leads to progressive muscle weakness and a premature death due to cardiorespiratory dysfunction. The mdx
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02.03.2022

Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation

Authors Laubrock K, von Loesch T, Steinmetz M, Lotz J, Frahm J, Uecker M, Unterberg-Buchwald C Journal European Journal of Radiology Open Citation Eur J Radiol Open. 2022 Mar 2;9:100404. Abstract Objectives: Quantitative evaluations of function, volume and mass are fundamental in the diagnostic workup of different cardiovascular diseases and
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