Research Alliance

Authors Kraxner J, Köster S Journal Biological Chemistry Citation Biol Chem. 2023 Apr 20. Abstract The cytoskeleton of eukaryotes consists of actin filaments, microtubules and intermediate filaments (IF). IFs, in particular, are prone to pronounced phosphorylation, leading to additional charges on the affected amino acids. In recent years, a variety

Authors Lenner N, Häring M, Eule S, Großhans J, Wolf F Journal ArXiv Citation arXiv:2304.09719. Abstract Finite time convergence to functionally important target states is a key component of many biological processes. We previously found that the terminal approach phase of such dynamics exhibits universal types of stochastic dynamics that

Authors Nanadikar MS, Vergel Leon AM, Guo J, van Belle GJ, Jatho A, Philip ES, Brandner AF, Böckmann RA, Shi R, Zieseniss A, Siemssen CM, Dettmer K, Brodesser S, Schmidtendorf M, Lee J, Wu H, Furdui CM, Brandenburg S, Burgoyne JR, Bogeski I, Riemer J, Chowdhury A, Rehling P, Bruegmann

Authors Kim D, Stoldt S, Weber M, Jakobs S, Belov VN, Hell SW   Journal Chemistry Methods   Citation Chem. Methods 2023, e202200076.   Abstract Disulfonated rhodamines are photostable and bright dyes widely used in life science and optical microscopy. However, di-sulfonated dyes were considered cell impermeable and not applicable

Authors Frost J, Schmitzer B, Töpperwien M, Eckermann M, Franz J, Stadelmann C, Salditt T Journal Neuroscience Citation Neuroscience. 2023 Apr 13:S0306-4522(23)00161-6. Abstract We investigate structural properties of neurons in the granular layer of human cerebellum with respect to their involvement in multiple sclerosis (MS). To this end we analyze

Authors Khan A, Markus AM, Svetlove A, Hülsmann S, Alves F, Dullin C Journal Research Square Citation Research Square, 12 April 2023, preprint. Abstract Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive, incurable, and debilitating fibrotic disease. Nintedanib – an oral tyrosine kinase inhibitor – significantly slows the IPF

Authors Volpe G, Maragò OM, Rubinzstein-Dunlop H, Pesce G, Stilgoe AB, Volpe G, Tkachenko G, Truong VG, Chormaic SN, Kalantarifard F, Elahi P, Käll M, Callegari A, Marqués MI, Neves AAR, Moreira WL, Fontes A, Cesar CL, Saija R, Saidi A, Beck P, Eismann JS, Banzer P, Fernandes TFD, Pedaci

Authors Weichard I, Taschenberger H, Gsell F, Bornschein G, Ritzau-Jost A, Schmidt H, Kittel RJ, Eilers J, Neher E, Hallermann S, Nerlich J   Journal BioRxiv   Citation bioRxiv 2023.04.11.535831.   Abstract Pre- and postsynaptic forms of long-term potentiation (LTP) are candidate synaptic mechanisms underlying learning and memory. At layer

Authors Lenner N, Häring M, Eule S, Großhans J, Wolf F   Journal ArXiv   Citation arXiv:2304.04279.   Abstract The dynamics of living systems often serves the purpose of reaching functionally important target states. We previously proposed a theory to analyze stochastic biological dynamics evolving towards target states in reverse

Authors Dervişoğlu R, Antonschmidt L, Nimerovsky E, Sant V, Kim M, Ryazanov S, Leonov A, Carlos Fuentes-Monteverde J, Wegstroth M, Giller K, Mathies G, Giese A, Becker S, Griesinger C, Andreas LB Journal Methods Citation Methods. 2023 Apr 8:S1046-2023(23)00056-7. Abstract Small molecules that bind to oligomeric protein species such as