Research Alliance

Authors Thirumalai A, Henseler J, Enayati M, Kusch K, Hessler R, Moser T, Huet AT Journal Theranostics Citation Theranostics 2025; 15(10):4270-4286. Abstract Optogenetic stimulation has become a promising approach for restoring lost body function. For example, partial restoration of vision has been achieved in a blind patient and preclinical proof-of-concept

Authors Ainatzi S, Kaufmann SV, Silbern I, Georgiev SV, Lorenz S, Rizzoli SO, Urlaub H Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2025 Mar 13:100946. Abstract Neuronal communication relies on neurotransmitter release from synaptic vesicles (SVs), whose dynamics are controlled by Ca2+-dependent pathways, as many thoroughly studied phosphorylation

Authors da Silva Padilha M, Koyuncu S, Chabanis E, Ryazanov S, Leonov A, Vilchez S, Klein R, Giese A, Griesinger C, Dudanova I Journal BioRxiv Citation bioRxiv 2025.03.11.642540. Abstract Huntington′s disease (HD) is a debilitating hereditary movement disorder caused by a CAG repeat expansion in the huntingtin gene. HD is

Authors Karedla N, Schneider F, Enderlein J, Chen T Journal Angewandte Chemie (International ed. in Engl.) Citation Angew Chem Int Ed Engl. 2025 Mar 10:e202423784. Abstract Polymer-supported or tethered lipid bilayers serve as versatile platforms for mimicking plasma membrane structure and dynamics, yet the impact of polymer supports on lipid

Authors Schaeper JJ, Kampshoff CA, Wolf BJ, Roos L, Michanski S, Ruhwedel T, Eckermann M, Meyer A, Jeschke M, Wichmann C, Moser T, Salditt T Journal Scientific Reports Citation Sci Rep. 2025 Mar 7;15(1):7933. Abstract Multi-scale X-ray phase contrast tomography (XPCT) enables three-dimensional (3D), non-destructive imaging of intact small animal

Authors Hüselitz A, Li H, Munk A Journal Arxiv Citation arXiv:2503.05270. Abstract We consider the problem of sequential estimation of a single change point in a piecewise linear regression model under a Gaussian setup. We demonstrate that a certain CUSUM-type statistic attains the minimax optimal rates for localizing the change

Authors Sala FA, Ditter K, Dybkov O, Urlaub H, Hillen HS Journal Nature Communications Citation Nat Commun. 2025 Mar 6;16(1):2261. Abstract Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its

Authors Makkeh A, Graetz M, Schneider AC, Ehrlich DA, Priesemann V, Wibral M Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Mar 11;122(10):e2408125122. Abstract Despite the impressive performance of biological and artificial networks, an intuitive

Authors Li H, Liu Z, Munk A Journal Arxiv Citation arXiv:2503.03020. Abstract Modern large-scale data analysis increasingly faces the challenge of achieving computational efficiency as well as statistical accuracy, as classical statistically efficient methods often fall short in the first regard. In the context of testing monotonicity of a regression

Authors Do TT, Siegert A, Domart F, Hahn F, Zeising C, Muth SM, Pape C, Kusch K, Dresbach T, Rizzoli S, Petrovic A, Fernandez-Busnadiego R Journal BioRxiv Citation bioRxiv 2025.03.01.640558. Abstract Despite decades of intense research, the molecular organization of the synapse is not well understood. To address this issue,