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09.04.2026

In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation

Authors Du D, Albert L, Weitzel M, Eijsink LE, Cotroneo ER, Marzin D, Opazo F, Simeth NA Journal Angewandte Chemie (International ed. in Engl.) Citation Angew Chem Int Ed Engl. 2026 Apr 9:e6231674. Abstract Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts
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07.04.2026

Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies

Authors Sridhar S, Vystrčilová M, Khani MH, Karamanlis D, Schreyer HM, Ramakrishna V, Krüppel S, Zapp SJ, Mietsch M, Ecker AS, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2026 Apr 7;22(4):e1014157. Abstract Retinal ganglion cells, the output neurons of the vertebrate retina, often display nonlinear summation of
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02.04.2026

Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients

Authors Liutkute A, Berrandou TE, Kestel S, Schnelle M, Dschun O, Amedei HA, Neuenroth L, Rytkin E, Kyshynska O, Kensah G, El-Essawi A, Jebran AF, Danner BC, Baraki H, Kutschka I, Bremmer F, Urlaub H, Schmidt C, Bouatia-Naji N, Efimov IR, Brundel BJJM, Lenz C, Voigt N Journal Cardiovascular Research
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02.04.2026

Single nucleus RNA sequencing and functional in vivo studies reveal TCF21 as a protective regulator in cardiac fibrosis

Authors Azmain T, Tran DDH, Saifuddin AB, Xu X, Alnour F, Hasenfuß G, Hulshoff M, Eckhardt PL, Tan X, Zeisberg M, Hille SS, Müller OJ, Zeisberg EM Journal Cardiovascular Research Citation Cardiovasc Res. 2026 Apr 2:cvag050. Abstract Aims: Cardiac fibrosis remains a significant and currently untreatable contributor to mortality in
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31.03.2026

Keratin Cortex Stabilizes Cells and Cell-Cell Contacts at High Strains

Authors Meyer R, Unkelbach U, Jain P, Rölleke U, Schwarz N, Perez-Tirado A, Schepers AV, Geisler C, Janshoff A, Köster S Journal PRX Life Citation PRX Life 4, 013038. Abstract The eukaryotic cytoskeleton consists of three filament types: actin filaments, microtubules, and intermediate filaments (IFs). IF proteins are expressed in
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30.03.2026

FRMPD4, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss

Authors Liedtke D, Rak K, Schrode KM, Hehlert P, Chamanrou N, Bengl D, Katana R, Heydaran S, Doll J, Han M, Nanda I, Senthilan PR, Jürgens L, Bieniussa L, Voelker J, Neuner C, Hofrichter MAH, Schröder J, Schellens RTW, de Vrieze E, van Wijk E, Zechner U, Herms S, Hoffmann
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30.03.2026

Fast-scanning small-angle X-ray scattering of hydrated biological cells

Authors Yu B, Sinha M, Da Silva RM, Rölleke U, Burghammer M, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Radiat. 2026 May 1. Abstract Due to their high penetration depth, X-rays enable us to obtain information from the interior of whole unsliced cells. Scanning small-angle X-ray scattering
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28.03.2026

Generation of marmoset monkeys with a non-mosaic disruption of the OTOF gene as a model of human deafness

Authors Kahland T, Lindenwald DL, Jeschke M, Kusch K, Tkachenko Eikel O, Uhl M, Rüger N, Drummer C, Wolf B, Benseler F, Brose N, Behr R, Moser T Journal Nature Communications Citation Nat Commun 17, 3033 (2026). Abstract Disabling hearing impairment is a common human sensory deficit. OTOF is a
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26.03.2026

Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction

Authors Wegener JB, Zühlke Y, Fleischhacker C, Marks J, Foo B, Bader N, Riedemann GC, Wedemeyer J, Vu KC, Vergel Leon AM, Paulke NJ, Kohl T, Urlaub H, Schmidt C, Hasenfuß G, Moser T, Rog-Zielinska EA, Lenz C, Lehnart SE, Brandenburg S Journal Scientific Reports Citation Sci Rep. 2026 Mar
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25.03.2026

lncRNA Glelr modulates microglia inflammatory programs in association with PU.1

Authors Pradhan R, Sakib MS, Kaurani L, Krüger DM, Pena T, Burkhardt S, Schütz AL, Kronenberg-Versteeg D, Delalle I, Sananbenesi F, Fischer A Journal Neurobiology of Disease Citation Neurobiol Dis. 2026 Mar 25;222:107366. Abstract Long non-coding RNAs (lncRNAs) are emerging as key regulators of brain function, but their contribution to
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