2025

Home >> Publications >> Release Date >> 2025 >> Seite 12
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03.06.2025

Learning to cluster neuronal function

Authors Nellen NS, Turishcheva P, Vystrčilová M, Sridhar S, Gollisch T, Tolias AS, Ecker AS Journal Arxiv Citation arXiv:2506.03293. Abstract Deep neural networks trained to predict neural activity from visual input and behaviour have shown great potential to serve as digital twins of the visual cortex. Per-neuron embeddings derived from
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01.06.2025

Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation

Authors Han M, Frieg B, Matthes D, Leonov A, Ryazanov S, Giller K, Nimerovsky E, Stampolaki M, Xue K, Overkamp K, Dienemann C, Riedel D, Giese A, Becker S, de Groot BL, Schröder GF, Andreas LB, Griesinger C Journal Nature Communication Citation Nat Commun. 2025 Oct 3;16(1):8850. Abstract Alzheimer’s disease
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29.05.2025

Detection and inference of changes in high-dimensional linear regression with non-sparse structures

Authors Cho H, Kley T, Li H Journal Journal of the Royal Statistical Society, Series B Citation Journal of the Royal Statistical Society Series B: Statistical Methodology, Volume 87, Issue 5, November 2025, Pages 1528–1552. Abstract For data segmentation in high-dimensional linear regression settings, the regression parameters are often assumed
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28.05.2025

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors

Authors Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R Journal Acta Crystallographica Section D-Structural Biology Citation Acta Crystallogr D Struct Biol. 2025 Jun 1. Abstract The SARS-CoV-2 helicase NSP13 is a highly conserved and essential component of the viral replication machinery, making it a promising target
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28.05.2025

Structural insights into lipid membrane binding by human ferlins

Authors Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J Journal EMBO Journal Citation EMBO J. 2025 May 28. Abstract Ferlins are ancient membrane proteins with a unique architecture, and play central roles in crucial processes that involve Ca2+-dependent vesicle fusion. Despite their links to
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27.05.2025

Success rates of simulated multi-pulse defibrillation protocols are sensitive to application timing with individual, protocol-specific optimal timings

Authors Aron M, Luther S, Parlitz U Journal Frontiers in Network Physiology Citation Front Netw Physiol. 2025 May 27;5:1572834. Abstract Ventricular fibrillation is a lethal condition where the heartbeat becomes too disorganised to maintain proper circulation. It is treated with defibrillation, which applies an electric shock in an attempt to
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27.05.2025

Toward elucidating the mechanism of cochlear stimulation by infrared light

Authors Moser T, Roos L Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2507582122. Abstract No abstract available. DOI 10.1073/pnas.2507582122   Pubmed Link
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22.05.2025

Silencing mitochondrial gene expression in living cells

Authors Cruz-Zaragoza LD, Dahal D, Koschel M, Boshnakovska A, Zheenbekova A, Yilmaz M, Morgenstern M, Dohrke JN, Bender J, Valpadashi A, Henningfeld KA, Oeljeklaus S, Kremer LS, Breuer M, Urbach O, Dennerlein S, Lidschreiber M, Jakobs S, Warscheid B, Rehling P Journal Science Citation Science. 2025 May 22:eadr3498. Abstract Mitochondria
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22.05.2025

Endogenous SNAP-tagging of Munc13-1 for monitoring synapse nanoarchitecture

Authors Kowald M, Bachollet SPJT, Benseler F, Steinecker M, Boll M, Kaushik S, Soykan T, Sun S, Birke R, Ilic D, Brose N, Hörnberg H, Lehmann M, Rizzoli SO, Broichhagen J, Lipstein N Journal JACS Au Citation JACS Au 2025. Abstract Synaptic function is governed by highly regulated protein machineries,
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21.05.2025

SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart

Authors Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS Journal Cell Reports Citation Cell Reports, Volume 44, Issue 6, 115723. Abstract Mitochondria are key to cellular energetics, metabolism,
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