Latest Publications

Authors Frieg B, Han M, Giller K, Dienemann C, Riedel D, Becker S, Andreas LB, Griesinger C, Schröder GF Journal Nature Communications Citation Nat Commun. 2024 Feb 13;15(1):1297. Abstract Alzheimer’s disease (AD) is a progressive and incurable neurodegenerative disease characterized by the extracellular deposition of amyloid plaques. Investigation into the

Authors Gotthardt M, Lehnart SE   Journal Cardiovascular Research   Citation Cardiovasc Res. 2024 Feb 9:cvae030.   Abstract No abstract available.   DOI 10.1093/cvr/cvae030   Pubmed Link

Authors Düring J, Wolter M, Toplak JJ, Torres C, Dybkov O, Fokkens TJ, Bohnsack KE, Urlaub H, Steinchen W, Dienemann C, Lorenz S   Journal Nature Structural & Molecular Biology   Citation Nat Struct Mol Biol (2024).   Abstract Ubiquitin ligases (E3s) are pivotal specificity determinants in the ubiquitin system

Authors Wang X, Scholand N, Tan Z, Mackner D, Telezki V, Blumenthal M, Schaten P, Uecker M Journal Arxiv Citation arXiv:2402.05366. Abstract Purpose: To develop a model-based nonlinear reconstruction for simultaneous water-specific T1, R∗2, B0 field and/or fat fraction (FF) mapping using single-shot inversion-recovery (IR) multi-echo radial FLASH. Methods: The

Authors Shein M, Hitzenberger M, Cheng T, Rout S, Leitl K, Sato Y, Zacharias M, Sakata E, Schuetz A Journal Nature Chemistry Citation Nat. Chem. (2024). Abstract The human enzyme p97 regulates various cellular pathways by unfolding hundreds of protein substrates in an ATP-dependent manner, making it an essential component

Authors Schmoll KA, Mager T, Tse TP, Alameldeen A, Zimmermann WH, Zafeiriou MP Journal Stem Cell Research Citation Stem Cell Res. 2024 Jan 28;75:103317. Abstract Control of neuronal activity by optogenetic tools is increasingly explored in disease modelling and optogenetics and holds great promise for regenerative therapy. To investigate neuronal

Authors Seibertz F, Voigt N Journal American Journal of Physiology: Heart and Circulatory Physiology Citation Am J Physiol Heart Circ Physiol. 2024 Jan 26. Abstract Personalized medicine refers to the tailored application of medical treatment at an individual level, taking into account the specific genotype or phenotype of each patient

Authors Alfken J, Neuhaus C, Major A, Taskina A, Hoffmann C, Ganzella M, Petrovic A, Zwicker D, Fernández-Busnadiego R, Jahn R, Milovanovic D, Salditt T Journal European Physical Journey. E, Soft Matter Citation Eur Phys J E Soft Matter. 2024 Jan 25;47(1):8. Abstract We study the formation of vesicle condensates

Authors Bloothooft M, Verbruggen B, Seibertz F, van der Heyden MAG, Voigt N, de Boer TP Journal Frontiers in Physiology Citation Front Physiol. 2024 Jan 24;15:1298340. Abstract Background: The rapid delayed rectifier potassium current (IKr) is important for cardiac repolarization and is most often involved in drug-induced arrhythmias. However, accurately

Authors Schmidt J, Kaulfuß S, Ott H, Gaubert M, Reintjes N, Bremmer F, Dreha-Kulaczewski S, Stroebel P, Yigit G, Wollnik B Journal Human Genetics Citation Hum Genet. 2024 Jan 24. Abstract The fibroblast growth factor receptors comprise a family of related but individually distinct tyrosine kinase receptors. Within this family,