Latest Publications

Authors Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmuller J, Nurnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S Journal Human Genetics Citation Hum Genet. Online ahead of print Abstract We report truncating de novo variants in specific exons of

Authors Komorowski K, Schaeper J, Sztucki M, Sharpnack L, Brehm G, Köster S, Salditt T Journal Soft Matter Citation Soft Matter. 2020 May 6;16(17):4142-4154. Abstract We have used time-resolved small-angle X-ray scattering (SAXS) to study the adhesion of lipid vesicles in the electrostatic strong-coupling regime induced by divalent ions. The

Authors Behr M, Ansari MA, Munk A , Holmes C Journal Proceedings of the National Academy of Sciences of the United States of America Citation PNAS May 5, 2020 117 (18) 9787-9792. Abstract Tree structures, showing hierarchical relationships and the latent structures between samples, are ubiquitous in genomic and biomedical

Authors Dieter A, Keppeler D, Moser T Journal Cell Reports Citation EMBO Mol Med 2020 Apr 7;12(4):e11618. Abstract Cochlear implants (CIs) are considered the most successful neuroprosthesis as they enable speech comprehension in the majority of half a million CI users suffering from sensorineural hearing loss. By electrically stimulating the

Authors Joppe K, Nicolas JD, Grünewald TA, Eckermann M, Salditt T, Lingor P Journal Biomedical Optics Express Citation Biomed. Opt. Express. 2020 11(4). Abstract In this work we use scanning X-ray microscopy to study the structure and elemental composition of neuromelanin-positive neurons in substantia nigra tissue of Parkinson patients (PD) and controls.

Authors Maus L, Lee C, Altas B, Sertel SM, Weyand K, Rizzoli SO, Rhee J, Brose N, Imig C, Cooper BH Journal Cell Reports Citation Cell Rep. 2020 Mar 17;30(11):3632-3643.e8. Abstract Purpose: Although similar in molecular composition, synapses can exhibit strikingly distinct functional transmitter release and plasticity characteristics. To determine

Authors Reichardt M, Frohn J, Khan A, Alves F, Salditt T Journal Biomedical Optics Express Citation Biomed Opt Express. 2020 May 1; 11(5): 2633–2651. Abstract The spatial organization of cardiac muscle tissue exhibits a complex structure on multiple length scales, from the sarcomeric unit to the whole organ. Here we

Authors Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, Arai N, Ohtake F, Murata S, Inada T, Baumeister W, Fernandez-Busnadiego R, Tanaka K, Saeki Y Journal Nature Citation Nature. 2020 Feb;578(7794):296-300. Abstract The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation