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10.10.2024

NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals

Authors Mougios N, Cotroneo ER, Imse N, Setzke J, Rizzoli S, Simeth NA, Tsukanov R, Opazo F Journal Nature Communications Citation Nat Commun. 2024 Oct 10;15(1):8771. Abstract Fluorescence microscopy has long been a transformative technique in biological sciences. Nevertheless, most implementations are limited to a few targets, which have been
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09.10.2024

One-step nanoscale expansion microscopy reveals individual protein shapes

Authors Shaib AH, Chouaib AA, Chowdhury R, Altendorf J, Mihaylov D, Zhang C, Krah D, Imani V, Spencer RKW, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawieh MM, Alawar N, Eilts J, Kang J, Soleimani A, Müller M, Pape
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08.10.2024

Cardiac arrhythmias: the growing role of autoantibodies in diagnosis and treatment

Authors Fakuade FE, Grune J, Voigt N Journal European Heart Journal Citation Eur Heart J. 2024 Oct 8:ehae648. Abstract No abstract available. DOI 10.1093/eurheartj/ehae648   Pubmed Link
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05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
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04.10.2024

Structural basis of Nipah virus replication

Authors Sala FA, Ditter K, Dybkov O, Urlaub H, Hillen HS Journal BioRxiv Citation bioRxiv 2024.10.04.616610. Abstract Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its RNA-dependent RNA polymerase (RdRp)
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03.10.2024

Membrane tension regulation is required for wound repair

Authors Raj N, Weiss M, Vos BE, Weischer S, Brinkmann F, Betz T, Trappmann B, Gerke V Journal Advanced Science Citation Adv Sci (Weinh). 2024 Oct 3:e2402317. Abstract Disruptions of the eukaryotic plasma membrane due to chemical and mechanical challenges are frequent and detrimental and thus need to be repaired
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01.10.2024

Super-Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live-cells

Authors Wang DX, Kong DM, Enderlein J, Chen T Journal BioRxiv Citation bioRxiv 2024.10.01.615997. Abstract Cell mechanics play a pivotal role in regulating numerous biological processes. While super-resolution microscopy enables the imaging of cellular forces in the lateral dimension with sub-10-nanometer resolution, achieving comparable resolution along the axial dimension remains
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27.09.2024

Measuring 3-dimensional dynamics of membrane in living cell with metal-induced energy transfer imaging/spectroscopy

Authors Chen T, Gallea JI, Karedla N, Wang D, Enderlein J Journal BioRxiv Citation bioRxiv 2024.09.27.614973. Abstract The dynamics of cellular membranes are crucial for many essential cellular processes. Despite various methods available to study membrane dynamics, simultaneously measuring membrane diffusion and fluctuations within living cell membranes remains challenging. In
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25.09.2024

BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

Authors Bergner CG, van der Meer F, Franz J, Vakrakou A, Würfel T, Nessler S, Schäfer L, Nau-Gietz C, Winkler A, Lagumersindez-Denis N, Wrzos C, Damkou IA, Sergiou C, Schultz V, Knauer C, Metz I, Bahn E, Rodriguez EG, Merkler D, Simons M, Stadelmann C Journal Brain Citation Brain. 2024
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25.09.2024

A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features

Authors Brücke C, Al-Azzani M, Ramalingam N, Ramón M, Sousa RL, Buratti F, Zech M, Sicking K, Amaral L, Gelpi E, Chandran A, Agarwal A, Chaves SR, Fernández CO, Dettmer U, Lautenschläger J, Zweckstteter M, Fernandez Busnadiego R, Zimprich A, Outeiro TF Journal MedRxiv Citation medRxiv 2024.09.23.24313864. Abstract Background: Parkinson’s
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