2026

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30.03.2026

Fast-scanning small-angle X-ray scattering of hydrated biological cells

Authors Yu B, Sinha M, Da Silva RM, Rölleke U, Burghammer M, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Radiat. 2026 May 1. Abstract Due to their high penetration depth, X-rays enable us to obtain information from the interior of whole unsliced cells. Scanning small-angle X-ray scattering
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28.03.2026

Generation of marmoset monkeys with a non-mosaic disruption of the OTOF gene as a model of human deafness

Authors Kahland T, Lindenwald DL, Jeschke M, Kusch K, Tkachenko Eikel O, Uhl M, Rüger N, Drummer C, Wolf B, Benseler F, Brose N, Behr R, Moser T Journal Nature Communications Citation Nat Commun 17, 3033 (2026). Abstract Disabling hearing impairment is a common human sensory deficit. OTOF is a
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26.03.2026

Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction

Authors Wegener JB, Zühlke Y, Fleischhacker C, Marks J, Foo B, Bader N, Riedemann GC, Wedemeyer J, Vu KC, Vergel Leon AM, Paulke NJ, Kohl T, Urlaub H, Schmidt C, Hasenfuß G, Moser T, Rog-Zielinska EA, Lenz C, Lehnart SE, Brandenburg S Journal Scientific Reports Citation Sci Rep. 2026 Mar
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25.03.2026

lncRNA Glelr modulates microglia inflammatory programs in association with PU.1

Authors Pradhan R, Sakib MS, Kaurani L, Krüger DM, Pena T, Burkhardt S, Schütz AL, Kronenberg-Versteeg D, Delalle I, Sananbenesi F, Fischer A Journal Neurobiology of Disease Citation Neurobiol Dis. 2026 Mar 25;222:107366. Abstract Long non-coding RNAs (lncRNAs) are emerging as key regulators of brain function, but their contribution to
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24.03.2026

A correlative workflow for synaptic imaging by cryo-electron tomography

Authors Do TT, Siegert A, Domart F, Hahn F, Zeising C, Muth S, Pape C, Kusch K, Dresbach T, Rizzoli SO, Petrovic A, Fernández-Busnadiego R Journal Structure Citation Structure. 2026 Mar 24:S0969-2126(26)00059-6. Abstract Despite decades of intense research, the molecular organization of the synapse is not well understood. To address
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23.03.2026

Persistence of vestibular function in the absence of glutamatergic transmission from hair cells

Authors Mukhopadhyay M, Modgekar R, Yang-Hood A, Ohlemiller KK, Militchin V, Xiao M, Shen Z, Rensing NR, Wong M, Lee SJ, Seal RP, Holt JC, Warchol ME, Maloney SE, Yuede CM, Rutherford MA, Pangrsic T Journal Scientific Reports Citation Sci Rep. 2026 Mar 23. Abstract Quantal synaptic transmission in vestibular
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20.03.2026

Evaluating Vision Foundation Models for Pixel and Object Classification in Microscopy

Authors Teuber C, Archit A, Boothe T, Ditte P, Rink J, Pape C Journal Arxiv Citation arXiv:2603.19802. Abstract Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level classification (object classification),
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19.03.2026

Spatial Adaptation of Primate Retinal Ganglion Cells between Artificial and Natural Stimuli

Authors Vystrčilová M, Sridhar S, Burg MF, Khani MH, Karamanlis D, Schreyer HM, Ramakrishna V, Krüppel S, Zapp SJ, Mietsch M, Gollisch T, Ecker AS Journal eNeuro Citation eNeuro. 2026 Mar 19:ENEURO.0060-26.2026. Abstract The retina encodes a broad range of stimuli, adapting its computations to features like brightness, contrast, and
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Prof. Dr. Melina Schuh © Irene Böttcher-Gajewski / Max-Planck-Institut für Multidisziplinäre Naturwissenschaften.

18.03.2026

Leopoldina zeichnet Biochemikerin Melina Schuh mit der Carus-Medaille aus

Um Paare mit unerfülltem Kinderwunsch unterstützen zu können, muss die Herausbildung der menschlichen Keimzellen genau verstanden werden. Die Biochemikerin und MBExC Mitglied Melina Schuh erforscht die Entwicklung von Säugetier-Eizellen und fand heraus, wieso es zu Fehlern bei der Eizellbildung kommen kann. Hierfür würdigt sie die Nationale Akademie der Wissenschaften Leopoldina
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18.03.2026

Revisiting foundation models for cell instance segmentation

Authors Archit A, Pape C Journal Arxiv Citation arXiv:2603.17845. Abstract Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy data. Recently, SAM2 and SAM3 have
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