Research Alliance

Authors Xiong L, Tolen EA, Choi J, Velychko S, Caizzi L, Velychko T, Adachi K, MacCarthy CM, Lidschreiber M, Cramer P, Schoeler HR Journal eLife Citation eLife 11:e71533. Abstract The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not

Authors Zimmermann WH Journal Science Citation Science. 2022 May 27;376(6596):917-918. Abstract A resorbable closed-loop sensor-actuator implant can temporarily control heart rate. DOI 10.1126/science.abq0605 Pubmed Link  

Authors Ghosh S, Hollingsworth JA, Gallea JI, Majumder S, Enderlein J, Chizhik AI Journal Nanotechnology Citation Nanotechnology. 2022 Jun 15;33(36). Abstract We report on proof of principle measurements of a concept for a super-resolution imaging method that is based on excitation field density-dependent lifetime modulation of semiconductor nanocrystals. The prerequisite

Authors Garrido-Charles A, Huet AT, Matera C, Thirumalai A, Hernando J, Llebaria A, Moser T, Gorostiza P Journal Journal of the American Chemical Society Citation J Am Chem Soc. 2022 May 18. Abstract Artificial control of neuronal activity enables studies of neural circuits and restoration of neural function. Direct, rapid,

Authors Dombrowski M, Engeholm M, Dienemann C, Dodonova, S. Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol 29, 493–501 (2022). Abstract Throughout the genome, nucleosomes often form regular arrays that differ in nucleosome repeat length (NRL), occupancy of linker histone H1 and transcriptional activity. Here,

Authors Schaffner SL, Wassouf Z, Lazaro DF, Xylaki M, Gladish N, Lin DTS, MacIsaac J, Ramadori K, Hentrich T, Schulze-Hentrich JM, Outeiro TF, Kobor MS Journal Human Molecular Genetics Citation Hum Mol Genet. 2022 May 14:ddac104. Abstract Parkinson’s disease (PD) is a neurological disorder with complex interindividual etiology that is

Authors Bali B, Gruber-Dujardin E, Kusch K, Rankovic V, Moser T Journal Life Science Alliance Citation Life Sci Alliance. 2022 May 5;5(8):e202101338 Abstract AAV-mediated optogenetic neural stimulation has become a clinical approach for restoring function in sensory disorders and feasibility for hearing restoration has been indicated in rodents. Nonetheless, long-term

Authors Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, Kügler S Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2022 May 3;15:868790. Abstract α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson’s disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are

Authors Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, Łyszkiewicz M, Ziȩtara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C Journal Journal of Clinical Investigation Citation J Clin Invest. 2022 May 2;132(9):e153153. Abstract The relevance

Authors Chegão A, Guarda M, Alexandre BM, Shvachiy L, Temido-Ferreira M, Marques-Morgado I, Fernandes Gomes B, Matthiesen R, Lopes LV, Florindo PR, Gomes RA, Gomes-Alves P, Coelho JE, Outeiro TF, Vicente Miranda H Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2022 Apr 25;8(1):51. Abstract Alpha-synuclein (aSyn) is a central