Release Date

Authors Bäuerlein FJB, Fernandez-Busnadiego R, Baumeister W Journal Trends in Cell Biology Citation Trends Cell Biol. 2020 Dec;30(12):951-966. Abstract Neurodegenerative diseases affect the lives of millions of people across the world, being particularly prevalent in the aging population. Despite huge research efforts, conclusive insights into the disease mechanisms are still

Authors Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N Journal Basic Research in Cardiology Citation Basic Res Cardiol. 2020 Nov 30;115(6):72. Abstract The molecular mechanisms underlying atrial fibrillation (AF), the most common form of arrhythmia, are poorly understood and therefore target-specific treatment options remain an unmet clinical need.

Authors Meinhardt J, Radke J, Dittmayer C, Mothes R, Franz J, Laue M, Schneider J, Brünink S, Hassan O, Stenzel W, Windgassen M, Rößler L, Goebel HH, Martin H, Nitsche A, Schulz-Schaeffer WJ, Hakroush S, Winkler MS, Tampe B, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Heppner BI, Stadelmann

Authors Qin S, Isbaner S, Gregor I, Enderlein J Journal Nature Protocols Citation Nat Protoc. 2020 Nov 27. Abstract Fluorescence microscopy has become an indispensable tool for cell biology. Recently, super-resolution methods have been developed to overcome the diffraction limit of light and have shown living cells in unprecedented detail.

Authors Hehlert P, Zhang W, Göpfert MC Journal Trends in Neurosciences Citation Trends Neurosci. 2020 Nov 27:S0166-2236(20)30251-4. Abstract Mechanosensation in Drosophila relies on sensory neurons transducing mechanical stimuli into ionic currents. The molecular mechanisms of this transduction are in the process of being revealed. Transduction relies on mechanogated ion channels

Authors Denz M, Marschall M, Herrmann H, Köster S Journal Soft Matter Citation Soft Matter. 2020 Nov 25. Abstract Vimentin intermediate filaments, together with actin filaments and microtubules, constitute the cytoskeleton in cells of mesenchymal origin. The mechanical properties of the filaments themselves are encoded in their molecular architecture and

Authors Thiele JC, Gregor I, Karedla N, Enderlein J Journal Physics of Fluids Citation Physics of Fluids 32, 112015 (2020). Abstract A large number of transport processes in physics, chemistry, and engineering are described by a convection–diffusion equation. This equation is notoriously difficult to solve due to the presence of

Authors Outeiro TF, Heutink P, Bezard E, Cenci AM Journal Movement Disorders Citation Mov Disord. 2020 Nov 16. Abstract Parkinson’s disease (PD) is primarily known as a movement disorder because of typical clinical manifestations associated with the loss of dopaminergic neurons in the substantia nigra. However, it is now widely

Authors Dominguez-Meijide A, Vasili E, Outeiro TF Journal Brain Science Citation Brain Sci. 2020 Nov 13;10(11):E858. Abstract Tauopathies are neurodegenerative disorders characterized by the deposition of aggregates composed of abnormal tau protein in the brain. Additionally, misfolded forms of tau can propagate from cell to cell and throughout the brain.

Authors del Alamo M, Li H, Munk A, Werner F Journal Algorithms Citation Algorithms 2020, 13(11), 296. Abstract Many modern statistically efficient methods come with tremendous computational challenges, often leading to large-scale optimisation problems. In this work, we examine such computational issues for recently developed estimation methods in nonparametric regression