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Authors Effertz T, Moser T, Oliver D Journal Faculty Reviews Citation Faculty Reviews  2020, 9:24. Abstract In recent years, genetics, physiology, and structural biology have advanced into the molecular details of the sensory physiology of auditory hair cells. Inner hair cells (IHCs) and outer hair cells (OHCs) mediate two key

Authors Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG Journal Nature

Authors Wittmeier A, Cassini C, Töpperwien M, Denz M, Hagemann J, Osterhoff M, Salditt T, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Rad (2021) 28. Abstract X-rays are emerging as a complementary probe to visible-light photons and electrons for imaging biological cells. By exploiting their small wavelength

Authors Glogger M, Spahn C, Enderlein J, Heilemann M Journal Angewandte Chemie (International Edition) Citation Angew Chem Int Ed Engl. 2020 Dec 10. Abstract Super‐resolution optical fluctuation imaging (SOFI) is a super‐resolution microscopy technique that overcomes the diffraction limit by analyzing intensity fluctuations of statistically independent emitters in a time

Authors Kraxner J, Lorenz C, Menzel J, Parfentev I, Silbern I, Denz M, Urlaub H, Schwappach B, Köster S Journal Nanoscale Citation Nanoscale. 2020 Dec 22. Abstract The mechanical properties of biological cells are determined by the cytoskeleton, a composite biopolymer network consisting of microtubules, actin filaments and intermediate filaments

Authors Outeiro TF Journal Journal of Neurochemistry Citation J Neurochem. 2020 Dec 9. Abstract Many different types of protein aggregates have attracted the minds and curiosity of countless armies of scientists, i.e., laboratories, in the world for more than 100 years. For example, it was in 1912 that F. Lewy

Authors Seefelder M, Alva V, Huang B, Engler T, Baumeister W, Guo Q, Fernández-Busnadiego R, Lupas AN, Kochanek S Journal BMC Evolutionary Biology Citation BMC Evol Biol. 2020 Dec 9;20(1):162. Abstract Background The huntingtin-associated protein 40 (HAP40) abundantly interacts with huntingtin (HTT), the protein that is altered in Huntington’s disease

Authors Schnabel F, Kamphausen SB, Funke R, Kaulfuß S, Wollnik B, Zenker M Journal American Journal of Medical Genetics Part A Citation Am J Med Genet A. 2020 Dec 7. Abstract Cell division cycle 42 (CDC42) is a small Rho GTPase, which serves as a fundamental intracellular signal node regulating

Authors Perego E, Reshetniak S, Lorenz C, Hoffmann C, Milovanovic D, Rizzoli S, Köster S Journal Scientific Reports Citation Sci Rep 10, 21086 (2020). Abstract Protein dynamics in the synaptic bouton are still not well understood, despite many quantitative studies of synaptic structure and function. The complexity of the synaptic

Authors Lavdovskaia E, Denks K, Nadler F, Steube E, Linden A, Urlaub H, Rodnina MV, Richter-Dennerlein R Journal Nucleic Acids Research Citation Nucleic Acids Res. 2020 Dec 2;gkaa1132. Abstract Translation and ribosome biogenesis in mitochondria require auxiliary factors that ensure rapid and accurate synthesis of mitochondrial proteins. Defects in translation