Release Date

Authors Fianu I, Chen Y, Dienemann Ch, Dybkov O, Linden A, Urlaub H, Cramer P Journal Science Citation Science. 2021 Nov 12;374(6569):883-887 Abstract Integrator and protein phosphatase 2A (PP2A) form a complex that dephosphorylates paused RNA polymerase II (Pol II), cleaves the nascent RNA, and terminates transcription. We report the

Authors Fomin A, Gärtner A, Cyganek L, Tiburcy M, Tuleta I, Wellers L, Folsche L, Hobbach AJ, von Frieling-Salewsky M, Unger A, Hucke A, Koser F, Kassner A, Sielemann K, Streckfuß-Bömeke K, Hasenfuss G, Goedel A, Laugwitz KL, Moretti A, Gummert JF, dos Remedios CG, Reinecke H, Knöll R, van

Authors Cappello S, Sung HM, Ickes C, Gibhardt CS, Vultur A, Bhat H, Hu Z, Brafford P, Denger A, Stejerean-Todoran I, Köhn RM, Lorenz V, Künzel N, Salinas G, Stanisz H, Legler T, Rehling P, Schön MP, Lang KS, Helms V, Herlyn M, Hoth M, Kummerow C, Bogeski I Journal

Authors Zelarayan L, Vendrell V, Domínguez-Frutos E, López-Hernández I, Schimmang-Alonso K, Alonso MT, Alvarez Y, Maier H, Anderson MJ, Lewandoski M, Schimmang T. Journal Developmental Dynamics Citation Dev Dyn. 2021 Oct 31. Abstract Background Fibroblast growth factors (Fgfs) are required for survival and organ formation during embryogenesis. Fgfs often execute

Authors Eisenberg-Bord M, Zung N, Collado J, Drwesh L, Fenech EJ, Fadel A, Dezorella N, Bykov YS, Rapaport D, Fernandez-Busnadiego R, Schuldiner M Journal Journal of Cell Biology Citation J Cell Biol. 2021 Nov 1;220(11):e202104100. Abstract Mitochondrial functions are tightly regulated by nuclear activity, requiring extensive communication between these organelles.

Authors Hurst S, Vos BE, Brandt M, Betz T Journal Nature Physics Citation Nat. Phys. (2021). Abstract The life and death of an organism rely on correct cell division, which occurs through the process of mitosis. Although the biochemical signalling and morphogenetic processes during mitosis are well understood, the importance

Authors Lipstein N, Chang S, Lin KH, López-Murcia FJ, Neher E, Taschenberger H, Brose N Journal Neuron Citation Neuron. 2021 Oct 21:S0896-6273(21)00727-3. Abstract During ongoing presynaptic action potential (AP) firing, transmitter release is limited by the availability of release-ready synaptic vesicles (SVs). The rate of SV recruitment (SVR) to release

Authors Moebel E, Martinez-Sanchez A, Lamm L, Righetto RD, Wietrzynski W, Albert S, Larivière D, Fourmentin E, Pfeffer S, Ortiz J, Baumeister W, Peng T, Engel BD, Kervrann C Journal Nature Methods Citation Nat Methods. 2021 Oct 21. Abstract Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of macromolecules

Authors Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P Journal Cell Citation Cell 2021 Oct 20. Abstract The human mitochondrial genome encodes thirteen core subunits of the oxidative phosphorylation system, and defects

Authors Khan A, Ramos-Gomes F, Markus A, Mietsch M, Hinkel R, Alves F Journal Biomedical Optics Express Citation Biomed. Opt. Express 12, 7009-7023 (2021). Abstract Heart failure is one of the most common causes of morbidity and mortality. Both maturational abnormalities and age-associated cardiac pathologies contribute to heart failure. Imaging-based