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Authors Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmuller J, Nurnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S Journal Human Genetics Citation Hum Genet. Online ahead of print Abstract We report truncating de novo variants in specific exons of

Authors Sograte-Idrissi S, Schlichthaerle T, Duque-Afonso CJ, Alevra M, Strauss S, Moser T, Jungmann R, Rizzoli SO, Opazo F Journal Nanoscale Citation Nanoscale. 2020 May 14;12(18):10226-10239. Abstract A standard procedure to study cellular elements is via immunostaining followed by optical imaging. This methodology typically requires target-specific primary antibodies (1.Abs), which

Authors Komorowski K, Schaeper J, Sztucki M, Sharpnack L, Brehm G, Köster S, Salditt T Journal Soft Matter Citation Soft Matter. 2020 May 6;16(17):4142-4154. Abstract We have used time-resolved small-angle X-ray scattering (SAXS) to study the adhesion of lipid vesicles in the electrostatic strong-coupling regime induced by divalent ions. The

Authors Jakobs S, Stephan T, Ilgen P, Brüser C Journal Annual Reviews of Biophysics Citation Annu Rev Biophys. 2020 May 6;49:289-308. Abstract Mitochondria are essential for eukaryotic life. These double-membrane organelles often form highly dynamic tubular networks interacting with many cellular structures. Their highly convoluted contiguous inner membrane compartmentalizes the

Authors Behr M, Ansari MA, Munk A , Holmes C Journal Proceedings of the National Academy of Sciences of the United States of America Citation PNAS May 5, 2020 117 (18) 9787-9792. Abstract Tree structures, showing hierarchical relationships and the latent structures between samples, are ubiquitous in genomic and biomedical

Authors Oleksiievets N, Thiele JC, Weber A, Gregor I, Nevskyi O, Isbaner S, Tsukanov R, Enderlein J Journal Journal of Physical Chemistry A Citation J Phys Chem A. 2020 Apr 30;124(17):3494-3500. Abstract Fluorescence lifetime imaging (FLIM) has become an important microscopy technique in bioimaging. The two most important of its applications are lifetime-multiplexing for imaging many different structures in

Authors Linden A, Deckers M, Parfentev I, Pflanz R, Homberg B, Neumann P, Ficner R, Rehling P, Urlaub H Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2020 Apr 24;mcp.RA120.002028. Abstract Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is currently receiving much attention. Not only

Authors Islam MR, Fischer A Journal Preprints Citation Preprints 2020, 2020040399. Abstract The recent outbreak of Coronavirus Disease 2019 (COVID-19) is a major threat to human health and the global economy. In addition to the development of vaccines there is an urgent need for preventive and therapeutic strategies towards severe

Authors Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P Journal Nature Citation Nature 580, 669–672 (2020). Abstract ‘Pioneer’ transcription factors are required for stem-cell pluripotency, cell differentiation and cell reprogramming1,2. Pioneer factors can bind nucleosomal DNA to enable gene expression from regions of the genome with closed chromatin.

Authors Zimmermann WH Journal Trends in Cardiovascular Medicine Citation Trends Cardiovasc Med 2020 Apr 8;S1050-1738(20)30049-9 Abstract no abstract available DOI 10.1016/j.tcm.2020.03.006 Pubmed Link