2021

Authors Hurst S, Vos BE, Brandt M, Betz T Journal Nature Physics Citation Nat. Phys. (2021). Abstract The life and death of an organism rely on correct cell division, which occurs through the process of mitosis. Although the biochemical signalling and morphogenetic processes during mitosis are well understood, the importance

Authors Lipstein N, Chang S, Lin KH, López-Murcia FJ, Neher E, Taschenberger H, Brose N Journal Neuron Citation Neuron. 2021 Oct 21:S0896-6273(21)00727-3. Abstract During ongoing presynaptic action potential (AP) firing, transmitter release is limited by the availability of release-ready synaptic vesicles (SVs). The rate of SV recruitment (SVR) to release

Authors Moebel E, Martinez-Sanchez A, Lamm L, Righetto RD, Wietrzynski W, Albert S, Larivière D, Fourmentin E, Pfeffer S, Ortiz J, Baumeister W, Peng T, Engel BD, Kervrann C Journal Nature Methods Citation Nat Methods. 2021 Oct 21. Abstract Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of macromolecules

Authors Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P Journal Cell Citation Cell 2021 Oct 20. Abstract The human mitochondrial genome encodes thirteen core subunits of the oxidative phosphorylation system, and defects

Authors Khan A, Ramos-Gomes F, Markus A, Mietsch M, Hinkel R, Alves F Journal Biomedical Optics Express Citation Biomed. Opt. Express 12, 7009-7023 (2021). Abstract Heart failure is one of the most common causes of morbidity and mortality. Both maturational abnormalities and age-associated cardiac pathologies contribute to heart failure. Imaging-based

Authors Bertero E, Nickel A, Kohlhaas M, Hohl M, Sequeira V, Brune C, Schwemmlein J, Abeßer M, Schuh K, Kutschka I, Carlein C, Münker K, Atighetchi S, Müller A, Kazakov A, Kappl R, von der Malsburg K, van der Laan M, Schiuma AF, Böhm M, Laufs U, Hoth M, Rehling

Authors Perera RP, Shaikhqasem A, Rostam N, Dickmanns A, Ficner R, Tittmann K, Dosch R Journal Biomolecules Citation Biomolecules. 2021; 11(10):1507. Abstract Many multicellular organisms specify germ cells during early embryogenesis by the inheritance of ribonucleoprotein (RNP) granules known as germplasm. However, the role of complex interactions of RNP granules

Authors Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimolgu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka

Authors Schmidt J, Schreiber G, Altmüller J, Thiele H, Nürnberg P, Li Y, Kaulfuß S, Funke R, Wilken B, Yigit G, Wollnik B Journal European Journal of Human Genetics Citation Eur J Hum Genet. 2021 Oct 11. Abstract Variants in transcription factor p63 have been linked to several autosomal dominantly

Authors Goldberg M, Islam MR, Kerimoglu C, Lancelin C, Gisa V, Burkhardt S, Krüger DM, Marquardt T, Malchow B, Schmitt A, Falkai P, Sananbenesi F, Fischer A Journal Translational Psychiatry Citation Transl Psychiatry. 2021 Oct 8;11(1):514. Abstract MicroRNAs have been linked to synaptic plasticity and memory function and are emerging