2020

Authors Jäckle K, Zeis T, Schaeren-Wiemers N, Junker A, van der Meer F, Kramann N, Stadelmann C, Brück W Journal Brain Citation Brain. 2020 Jul 1;143(7):2073-2088. Abstract Multiple sclerosis is an immune-mediated chronic inflammatory disease of the CNS that leads to demyelinated lesions in the grey and white matter. Inflammatory,

Authors Lemus-Diaz N, Ferreira RR, Bohnsack KE, Gruber J, Bohnsack MT Journal Nucleic Acids Research Citation Nucleic Acids Res. 2020;gkaa549. published online ahead of print, 2020 Jul 1. Abstract MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression and their dysfunction is often associated with cancer. Alongside the canonical miRNA

Authors Dieter A, Klein E, Keppeler D, Jablonski L, Harczos T, Hoch G, Rankovic V, Paul O, Jeschke M, Ruther P, Moser T Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2020 Jun 29;e12387. Abstract Electrical cochlear implants (eCIs) partially restore hearing and enable speech comprehension to more than half

Authors Jean P, Anttonen T, Michanski S, de Diego AMG, Steyer AM, Neef A, Oestreicher D, Kroll J, Nardis C, Pangršič T, Möbius W, Ashmore J, Wichmann C, Moser T Journal Nature Communications Citation Nat Comm. 2020 Jun 25;11(1):3208. Abstract Inner hair cells (IHCs) are the primary receptors for hearing.

Authors Stephan T, Bruser C, Deckers M, Steyer M, Balzarotti F, Barbot M, Behr TS, Heim G, Hubner W, Ilgen P, Lange F, Pacheu-Grau D, Pape JK, Stoldt S, Huser T, Hell SW, Möbius W, Rehling P, Riedel D, Jakobs S Journal EMBO Journal Citation EMBO J 2020 Jun 22;e104105

Authors Backhaus SJ, Lange T, Beuthner BE, Topci R, Wang X, Kowallick JT, Lotz J, Seidler T, Toischer K, Zeisberg EM, Puls M, Jacobshagen C, Uecker M, Hasenfuß G, Schuster A Journal Journal of Cardiovascular Magnetic Resonance Citation J Cardiovasc Magn Reson. 2020;22(1):46. Published 2020 Jun 22. Abstract Background: Myocardial

Authors Farnung L, Ochmann M, Cramer P Journal Elife Citation Elife. 2020;9:e56178. Published 2020 Jun 16. Abstract Chromatin remodeling plays important roles in gene regulation during development, differentiation and in disease. The chromatin remodeling enzyme CHD4 is a component of the NuRD and ChAHP complexes that are involved in gene

Authors Cassini C, Wittmeier A, Brehm G, Denz M, Burghammer M, Köster S Journal Journal of Synchrotron Radiation Citation J. Synchrotron Rad. (2020). 27, 1059–1068. Abstract X-ray imaging is a complementary method to electron and fluorescence microscopy for studying biological cells. In particular, scanning small-angle X-ray scattering provides overview images of whole cells

Authors Vos SM, Farnung L, Linden A, Urlaub H, Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol. 2020. Abstract Transcription by RNA polymerase II (Pol II) is carried out by an elongation complex. We previously reported an activated porcine Pol II elongation complex, EC*, encompassing

Authors Ganapathi M, Argyriou L, Martínez-Azorín F,  Morlot S, Yigit G, Lee TM,  Auber B, von Gise A, Petrey DS, Thiele H, Cyganek L, Sabater-Molina M, Ahimaz P, Cabezas-Herrera J, Sorlí-García M, Zibat A, Siegelin MD, Burfeind P, Buchovecky CM, Hasenfuss G, Honig B, Li Y, Iglesias AD, Wollnik B Journal Human Genetics Citation Hum Genet. 2020 Jun 8. Online ahead of print. Abstract Dilated cardiomyopathy (DCM) belongs to the most frequent forms of cardiomyopathy mainly characterized by