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01.04.2022

Selective optogenetic control of Gq signaling using human Neuropsin

Authors Wagdi A, Malan D, Sathyanarayanan U, Beauchamp JS, Vogt M, Zipf D, Beiert T, Mansuroglu B, Dusend V, Meininghaus M, Schneider L, Kalthof B, Wiegert JS, König GM, Kostenis E, Patejdl R, Sasse P, Bruegmann T Journal Nature Communications Citation Nat Commun. 2022 Apr 1;13(1):1765. Author Correction: Nat Commun.
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31.03.2022

Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease

Authors Dankovich TM, Rizzoli SO Journal Frontiers in Cellular Neuroscience Citation Front Cell Neurosci. 2022 Mar 31;16:854897. Abstract The extracellular matrix (ECM) stabilizes neural circuits and synapses in the healthy brain, while also retaining the ability to be remodeled, to allow synapses to be plastic. A well-described mechanism for ECM
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29.03.2022

Roles and dynamics of 3-methylcytidine in cellular RNAs

Authors Bohnsack KE, Kleiber N, Lemus-Diaz N, Bohnsack MT Journal Trends in Biochemical Sciences Citation Trends Biochem Sci. 2022 Mar 29:S0968-0004(22)00063-9. Abstract Modified nucleotides within cellular RNAs significantly influence their biogenesis, stability, and function. As reviewed here, 3-methylcytidine (m3C) has recently come to the fore through the identification of the
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28.03.2022

Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system

Authors Calapai A, Cabrera-Moreno J, Moser T, Jeschke M Journal Nature Communications Citation Nat Commun. 2022 Mar 28;13(1):1648. Abstract Devising new and more efficient protocols to analyze the phenotypes of non-human primates, as well as their complex nervous systems, is rapidly becoming of paramount importance. This is because with genome-editing
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21.03.2022

Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Authors Heo D, Ling JP, Molina-Castro GC, Langseth AJ, Waisman A, Nave KA, Möbius W, Wong PC, Bergles DE Journal Elife Citation eLife. 2022 Mar 21;11:e75230. Abstract Generation of oligodendrocytes in the adult brain enables both adaptive changes in neural circuits and regeneration of myelin sheaths destroyed by injury, disease,
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12.03.2022

Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene

Authors Pater JA, Penney C, O’Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble
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11.03.2022

Methods for multiscale structural and functional analysis of the mammalian cochlea

Authors Vogl C, Neef J, Wichmann C Journal Molecular and Cellular Neuroscience Citation Mol Cell Neurosci. 2022 Mar 11;120:103720. Abstract The mammalian cochlea is a snail-shaped structure deeply that is embedded in the temporal bone and harbors the auditory sensory epithelium – the organ of Corti. Since the discovery of
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10.03.2022

A mathematical model for electrical activity in pig atrial tissue

Authors Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Journal Frontiers in Physiology Citation Front Physiol. 2022 Mar 10;13:812535. Abstract State of the art mathematical models are currently used to bridge the gap between basic research conducted in the laboratory and preclinical research conducted on large
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08.03.2022

Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration

Authors Liu JK, Karamanlis D, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2022 Mar 8;18(3):e1009925. Abstract A central goal in sensory neuroscience is to understand the neuronal signal processing involved in the encoding of natural stimuli. A critical step towards this goal is the development of successful
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08.03.2022

A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease

Authors Shomroni O, Sitte M, Schmidt J, Parbin S, Ludewig F, Yigit G, Zelarayan LC, Streckfuss-Bömeke K, Wollnik B, Salinas G Journal Scientific Reports Citation Sci Rep. 2022 Mar 8;12(1):4091. Abstract Single cell multi-omics analysis has the potential to yield a comprehensive understanding of the cellular events that underlie the
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