Latest Publications

Authors Galbusera R, Weigel M, Bahn E, Schaedelin S, Cagol A, Lu PJ, Barakovic M, Melie-Garcia L, Franz J, Dechent P, Nair G, Kappos L, Brück W, Stadelmann C, Granziera C Journal Brain Pathology Citation Brain Pathol. 2025 Apr 14:e70010. Abstract Remyelination of cortical lesions in people with multiple sclerosis

Authors Garg P, Bähr M, Kügler S Journal Methods in Molecular Biology (Clifton, N.J.) Citation Methods Mol Biol. 2025;2910:53-68. Abstract Reprogramming of somatic cells like blood cells and fibroblasts to obtain human induced pluripotent stem cells (hiPSCs) has become a state-of-the-art tool to study human diseases. The self-renewable hiPSCs offer

Authors Kaurani L, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Krüger DM, Pena T, Heutink P, Sananbenesi F, Fischer A Journal Translational Psychiatry Citation Transl Psychiatry. 2025 Apr 11;15(1):142. Abstract Frontotemporal dementia is a debilitating neurodegenerative disorder characterized by frontal and temporal lobe degeneration, resulting in behavioral changes, language

Authors Yang Y, Wong MH, Huang X, Chiu DN, Liu YZ, Prabakaran V, Imran A, Panzeri E, Chen Y, Huguet P, Kunisky A, Ho J, Dong Y, Carter BC, Xu W, Schlüter OM Journal Science Advances Citation Sci Adv. 2025 Apr 11;11(15):eads5750. Abstract At synapses, miniature synaptic transmission forms the

Authors Jeremias J, Pape C Journal Methods in Microscopy Citation Methods in Microscopy, 2025. Abstract Counting objects is an important task in biomedical image analysis, for example to count cells in microscopy or microbial colonies in laboratory applications. Similar to most image analysis tasks, modern approaches to counting rely on

Authors Yigit G, Kaulfuß S, Wollnik B Journal Medizinische Genetik Citation Med Genet. 2025 Apr 8;37(2):103-111. Abstract Cardiomyopathies (CMs) are a clinically heterogeneous group of cardiovascular diseases characterized by structural and functional abnormalities of the heart muscle in the absence of coronary artery disease, hypertension, valve disease, or congenital heart

Authors Thongdee N, Alaniz MM, Samatova E, Zhong A, Esnault C, Zhang H, Dale RK, Rodnina MV, Storz G Journal Molecular Cell Citation Mol Cell. 2025 Mar 30:S1097-2765(25)00258-8. Abstract Most characterized interactions between bacterial small RNAs (sRNAs) and their target mRNAs occur near ribosome binding sites, resulting in changes in

Authors Stadelmann C, Franz J, Nessler S Journal Current Opinion in Neurology Citation Curr Opin Neurol. 2025 Apr 4. Abstract Purpose of review: Neuropathological studies in human brain tissue are indispensable for our understanding of disease mechanisms in multiple sclerosis (MS). They inform concepts of lesion evolution, tissue regeneration and

Authors Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli SO, Priesemann V Journal Communications Biology Citation Commun Biol. 2025 Apr 2;8(1):542. Abstract After synaptic transmission, fused synaptic vesicles are recycled, enabling the synapse to recover its capacity for renewed release. The recovery steps, which range from endocytosis to vesicle docking and

Authors Zipf D, Vogt M, Sathyanarayanan U, Wagdi A, Riebeling J, Patejdl R, Bruegmann T Journal Neurogastroenterology and Motility Citation Neurogastroenterol Motil. 2025 Mar 31:e70028. Abstract Background: Optogenetics is a cutting-edge approach that can enable direct stimulation of gastric smooth muscle cells (SMC) by combining cell-specific overexpression of light-sensitive proteins