Stadelmann-Nessler, Christine

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13.09.2023

Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?

Authors Thümmler K, Wrzos C, Franz J, McElroy D, Cole JJ, Hayden L, Arseni D, Schwarz F, Junker A, Edgar JM, Kügler S, Neef A, Wolf F, Stadelmann C, Linington C. Journal Neuropathology and Applied Neurobiology Citation Neuropathol Appl Neurobiol. 2023 Sep 13:e12935. Abstract Aims: Fibroblast growth factor (FGF) signalling
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09.09.2023

An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex

Authors Enz LS, Winkler A, Wrzos C, Dasen B, Nessler S, Stadelmann C, Schaeren-Wiemers N Journal International Journal of Molecular Sciences Citation Int J Mol Sci. 2023 Sep 9;24(18):13893. Abstract Modeling chronic cortical demyelination allows the study of long-lasting pathological changes observed in multiple sclerosis such as failure of remyelination,
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28.07.2023

Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson’s disease

Authors Warth Perez Arias CC, Silbern I, Caldi Gomes L, Wartmann H, Dambeck V, Fanz J, Neuenroth L, Bähr M, Outeiro TF, Bonn S, Stadelmann-Nessler C, Rizzoli SO, Lenz C, Urlaub H, Lingor P Journal Journal of Neurochemistry Citation J Neurochem. 2023 Jul 28. Abstract Parkinson’s disease (PD) affects a
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29.06.2023

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

Authors Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich
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13.04.2023

3d virtual histology reveals pathological alterations of cerebellar granule cells in multiple sclerosis

Authors Frost J, Schmitzer B, Töpperwien M, Eckermann M, Franz J, Stadelmann C, Salditt T Journal Neuroscience Citation Neuroscience. 2023 Apr 13:S0306-4522(23)00161-6. Abstract We investigate structural properties of neurons in the granular layer of human cerebellum with respect to their involvement in multiple sclerosis (MS). To this end we analyze
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03.04.2023

Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination

Authors Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D’Este E, Möbius W, Cordano C, Pröbstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank A, Cerina M, Müntefering T, Lerma-Martin C, Sonner JK, Sin JH, Disse P, Rychlik N, Sabeur K, Chavali M,
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08.12.2022

Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis

Authors Galbusera R, Bahn E, Weigel M, Schaedelin S, Franz J, Lu PJ, Barakovic M, Melie-Garcia L, Dechent P, Lutti A, Sati P, Reich DS, Nair G, Brück W, Kappos L, Stadelmann C, Granziera C. Journal Brain Pathology Citation Brain Pathol. 2022 Dec 8:e13136. Abstract Quantitative MRI (qMRI) probes the
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08.09.2022

The murine male reproductive organ at a glance: Three-dimensional insights and virtual histology using label-free light sheet microcopy

Authors Pinkert-Leetsch D, Rost JU, Schmiedeknecht MUH, Stadelmann C, Alves F, Missbach-Guentner J Journal Andrology Citation Andrology. 2022 Sep 8. Abstract Background: The unique anatomy of the male reproductive organ reflects its complex function from sperm maturation to their storage for months until emission. Since light microscopy in two dimensions
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30.06.2022

Distinct roles of the meningeal layers in CNS autoimmunity

Authors Merlini A, Haberl M, Strauß J, Hildebrand L, Genc N, Franz J, Chilov D, Alitalo K, Flügel-Koch C, Stadelmann C, Flügel A, Odoardi F Journal Nature Neuroscience Citation Nat Neurosci. 2022 Jun 30. Abstract The meninges, comprising the leptomeninges (pia and arachnoid layers) and the pachymeninx (dura layer), participate
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13.04.2022

Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS

Authors Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N, Kreutzfeldt M, Klimek B, Di Liberto G, Egervari K, Piccinno M, Shammas G, Mariotte A, Fonta N, Liaudet N, Shlesinger D, Liuzzi AR, Wagner I, Saadi C, Stadelmann C, Reddy S, Becher B, Merkler D Journal Science
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