Söding, Johannes

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15.04.2022

Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration

Authors Luebben AV, Bender D, Becker S, Crowther LM, Erven I, Hofmann K, Söding J, Klemp H, Bellotti C, Stäuble A, Qiu T, Kathayat RS, Dickinson BC, Gärtner J, Sheldrick GM, Krätzner R, Steinfeld R Journal Science Advances Citation Sci Adv. 2022 Apr 15;8(15):eabj8633. Abstract Genetic CLN5 variants are associated
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06.05.2021

Tejaas: reverse regression increases power for detecting trans-eQTLs

Authors Banerjee S, Simonetti FL, Detrois KE, Kaphle A, Mitra R, Nagial R, Söding J Journal Genome Biology Citation Genome Biol. 2021 May 6;22(1):142. Abstract Trans-acting expression quantitative trait loci (trans-eQTLs) account for ≥70% expression heritability and could therefore facilitate uncovering mechanisms underlying the origination of complex diseases. Identifying trans-eQTLs
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