Simeth, Nadja

Authors Cacciarini M, Woolley GA, Szymanski W, Simeth NA Journal Organic & Biomolecular Chemistry Citation Org Biomol Chem. 2025 Aug 18. Abstract No abstract available. DOI 10.1039/d5ob90098k   Pubmed Link  

Authors Imse B, Rojas L, Herrero CG, Thallmair S, Rhee JS, Simeth N Journal RSC Chemical Biology Citation RSC Chem Biol. 2025 Jul 19. Abstract Light-controlled molecules have become valuable tools for studying biological systems offering an unparalleled control in space and time. Specifically, the remote-controllable (de)activation of small molecules

Authors Jakob L, van der Wal JJ, Tovtik R, Copko J, Iagatti A, Donato MD, Crespi S, Simeth NA Journal Chemistry – A European Journal Citation Chemistry. 2025 Jul 1:e202501856. Abstract Photoswitches have been impacting diverse areas of research, introducing means of dynamically regulating their environment through reversible photochemical isomerization.

Authors Tovtik R, Marzin D, Weigel P, Crespi S, Simeth NA Journal Beilstein Journals of Organic Chemistry Citation Beilstein J Org Chem. 2025 Apr 25;21:830-838. Abstract Phenylazopyrazole photoswitches proved to be valuable structural motifs for various applications ranging from materials science to medicine. Despite their potential, their structural diversity is

Authors Cotroneo ER, Cheng TC, Kaltschnee L, Maibach P, Engelke M, Schwegler N, Thomas F, Thiele CM, Simeth N Journal ChemRxiv Citation ChemRxiv. 2025. Abstract Peptides and proteins, that have the tendency to form aggregates, are often discussed in the context of Alz-heimer’s, Huntington’s, or Parkinson’s disease. However, studying aggregation

Authors Mougios N, Cotroneo ER, Imse N, Setzke J, Rizzoli S, Simeth NA, Tsukanov R, Opazo F Journal Nature Communications Citation Nat Commun. 2024 Oct 10;15(1):8771. Abstract Fluorescence microscopy has long been a transformative technique in biological sciences. Nevertheless, most implementations are limited to a few targets, which have been

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling

Authors Chaudhuri A, Eijsink LE, Simeth NA Journal Chemical Communications (Cambridge) Citation Chem Commun (Camb). 2024 Aug 22. Abstract The dynamic regulation of pH via an external stimulus is an attractive technique to gate chemical transformations. Applying photons of different energy, we preferentially address either a photoacid or a photobase

Authors Fu Y, Simeth NA, Szymanski W, Feringa BL Journal Nature Reviews Chemistry Citation Nat Rev Chem. 2024 Aug 7. Abstract Photoclick reactions combine the advantages offered by light-driven processes, that is, non-invasive and high spatiotemporal control, with classical click chemistry and have found applications ranging from surface functionalization, polymer

Authors Lāce I, Bazzi S, Uranga J, Schirmacher A, Diederichsen U, Mata RA, Simeth NA Journal ChemBioChem Citation Chembiochem. 2023 May 22:e202300270. Abstract Peptide-protein interactions (PPIs) are facilitated by the well-defined three-dimensional structure of bioactive peptides, interesting compounds for the development of new therapeutic agents. Their secondary structure and thus