Moser, Tobias

Authors Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser T Journal Frontiers in Neuroscience Citation Front Neurosci. 2023 Jan 23;17:1105562. Abstract Background The electrical cochlear implant (eCI) partially restores hearing in individuals affected by profound hearing impairment (HI) or deafness. However, the limited resolution of sound frequency

Authors Mittring A, Moser T, Huet AT Journal Brain Stimulation Citation Brain Stimul. 2023 Jan 23:S1935-861X(23)01673-X. Abstract Optogenetic control of neural activity enables innovative approaches to improve functional restoration of diseased sensory and motor systems. For clinical translation to succeed, optogenetic stimulation needs to closely match the coding properties of

Authors Chakrabarti R, Jaime Tobón LM, Slitin L, Redondo-Canales M, Hoch G, Slashcheva M, Fritsch E, Bodensiek K, Özçete ÖD, Gültas M, Michanski S, Opazo F, Neef J, Pangrsic T, Moser T, Wichmann C Journal elife Citation Elife. 2022 Dec 23;11:e79494. Abstract RRibbon synapses of cochlear inner hair cells (IHCs)

Authors Helke C, Reinhardt M, Arnold M, Schwenzer F, Haase M, Wachs M, Goßler C, Götz J, Keppeler D, Wolf B, Schaeper J, Salditt T, Moser T, Schwarz UT, Reuter D Journal Materials (Basel) Citation Materials (Basel). 2022 Dec 22;16(1):106. Abstract Improved hearing restoration by cochlear implants (CI) is expected

Authors Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM Journal Developmental Dynamics Citation Dev Dyn. 2022 Oct 25. Abstract Background: Proper connectivity between type I spiral ganglion neurons (SGNs) and inner hair cells (IHCs) in the cochlea is

Authors Jaime Tobón LM, Moser T Journal Cell Reports Citation Cell Rep, 2022. under review. Abstract Synaptic heterogeneity can expand the encoding capacity of individual neurons or sensory cells. The afferent synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in the cochlea exhibit marked heterogeneity in structure

Authors Wolf BJ, Kusch K, Hunniford V, Vona B, Kühler R, Keppeler D, Strenzke N, Moser T Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2022 Jul 14:e15798. Abstract Hearing impairment, the most prevalent sensory deficit, affects more than 466 million people worldwide (WHO). We presently lack causative treatment for

Authors Khurana L, Keppeler D, Jablonski L, Moser T Journal Computational and Structural Biotechnology Journal Citation Comput Struct Biotechn J, 2022. Abstract When hearing fails, electrical cochlear implants (eCIs) partially restore hearing by direct stimulation of spiral ganglion neurons (SGNs). As light can be better confined in space than electrical

Authors Grabner CP, Jansen I, Neef J, Weihs T, Schmidt R, Riedel D, Wurm CA, Moser T Journal Science Advances Citation Sci Adv. 2022 Jul 15;8(28):eabl7560. Abstract Cells assemble macromolecular complexes into scaffoldings that serve as substrates for catalytic processes. Years of molecular neurobiology indicate that neurotransmission depends on such

Authors Garrido-Charles A, Huet AT, Matera C, Thirumalai A, Hernando J, Llebaria A, Moser T, Gorostiza P Journal Journal of the American Chemical Society Citation J Am Chem Soc. 2022 May 18. Abstract Artificial control of neuronal activity enables studies of neural circuits and restoration of neural function. Direct, rapid,