Moser, Tobias

Authors Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2023 Dec 19:100704. Abstract In the ear, inner hair cells (IHCs) employ sophisticated glutamatergic ribbon synapses with afferent neurons to transmit auditory

Authors Chen H, Fang Q, Benseler F, Brose N, Moser T Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2023 Dec 12;16:1299509. Abstract Afferent synapses of cochlear inner hair cells (IHCs) employ a unique molecular machinery. Otoferlin is a key player in this machinery, and its genetic defects cause

Authors Chen H, Monga M, Fang Q, Slitin L, Neef J, Chepurwar SS, Mingroni Netto RC, Lezirovitz K, Tabith A Jr, Benseler F, Brose N, Kusch K, Wichmann C, Strenzke N, Vona B, Preobraschenski J, Moser T Journal Protein & Cell Citation Protein & Cell. 2023 Dec 8:pwad058. accepted manuscript.

Authors Jaime Tobón LM, Moser T Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2311539120. Abstract In our hearing organ, sound is encoded at ribbon synapses formed by inner hair cells (IHCs) and spiral

Authors Moser T, Karagulyan N, Neef J, Jaime Tobon LM Journal EMBO Journal Citation EMBO J. 2023.e114587. Abstract Our sense of hearing enables the processing of stimuli that differ in sound pressure by more than six orders of magnitude. How to process a wide range of stimulus intensities with temporal

Authors Micheal M, Wolf BJ, Klinge-Strahl A, Jeschke M, Moser T, Dieter A Journal Brain Stimulation Citation Brain Stimul. 2023 Sep 29:S1935-861X(23)01920-4. Abstract Cochlear implants (CIs) restore activity in the deafened auditory system via electrical stimulation of the auditory nerve. As the spread of electric current in biological tissues is

Authors Karagulyan N, Moser T Journal Frontiers in Molecular Neuroscience – Molecular Signalling and Pathways Citation Front Mol Neurosci. 2023 Sep 6;16:1248941. Abstract Neural sound encoding in the mammalian cochlea faces the challenge of representing audible sound pressures that vary over six orders of magnitude. The cochlea meets this demand

Authors Khurana L, Harczos T, Moser T, Jablonski L Journal iScience Citation iScience (2023). Abstract In 2019, disabling hearing loss affected 430 million people worldwide and will reach over 700 million by 2050. Severe-to-complete sensorineural hearing loss is often treated by electrical cochlear implants (eCIs) bypassing dysfunctional or lost hair

Authors Michanski S, Kapoor R, Steyer A, Möbius W, Früholz I, Ackermann F, Gültas M, Garner CC, Hamra FK, Neef J, Strenzke N, Moser T, Wichmann C Journal Embo Reports Citation EMBO Reports (2023)e56702. Abstract Cochlear inner hair cells (IHCs) form specialized ribbon synapses with spiral ganglion neurons that tirelessly

Authors Zerche M, Wrobel C, Kusch K, Moser T, Mager T Journal Molecular Therapy: Methods and Clinical Development Citation Molecular Therapy: Methods & Clinical Development Vol. 29 June 2023. Abstract Sensory restoration by optogenetic neurostimulation provides a promising future alternative to current electrical stimulation approaches. So far, channelrhodopsins (ChRs) typically