Köster, Sarah

Authors Nageswaran S, Haipeter J, Bodenschatz JFE, Meyer R, Köster S, Steinem C Journal Biomacromolecules Citation Biomacromolecules. 2023 Jun 12;24(6):2512-2521. Abstract Within a cell, intermediate filaments interact with other cytoskeletal components, altogether providing the cell’s mechanical stability. However, little attention has been drawn to intermediate filaments close to the plasma

Authors Kraxner J, Köster S Journal Biological Chemistry Citation Biol Chem. 2023 Apr 20. Abstract The cytoskeleton of eukaryotes consists of actin filaments, microtubules and intermediate filaments (IF). IFs, in particular, are prone to pronounced phosphorylation, leading to additional charges on the affected amino acids. In recent years, a variety

Authors Burchert JP, Graceffa R, Saldanha O, Burghammer M, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Radiat. 2023 May 1. Abstract Owing to their large penetration depth and high resolution, X-rays are ideally suited to study structures and structural changes within intact biological cells. For this reason,

Authors Steyer AM, Buscham TJ, Lorenz C, Hümmert S, Eichel-Vogel MA, Schadt LC, Edgar JM, Köster S, Möbius W, Nave KA, Werner HB Journal Glia Citation Glia. 2022 Nov 10. Abstract Healthy myelin sheaths consist of multiple compacted membrane layers closely encasing the underlying axon. The ultrastructure of CNS myelin

Authors Lorenz C, Köster S Journal Biophysics Reviews Citation Biophysics Rev. 3, 031304 (2022) Abstract Different types of biological cells respond differently to mechanical stresses, and these responses are mainly governed by the cytoskeleton. The main components of this biopolymer network are actin filaments, microtubules, and intermediate filaments, whose mechanical

Authors Wittmeier A, Bernhardt M, Robisch A-L, Cassini C, Osterhoff M, Salditt T, Köster S Journal Biomedical Optics Express Citation Biomed. Opt. Express 13, 4954-4969 (2022) Abstract The function of a biological cell is fundamentally defined by the structural architecture of packaged DNA in the nucleus. Elucidating information about the

Authors Epple R, Krüger D, Berulava T, Brehm G, Ninov M, Islam R, Köster S, Fischer A Journal Molecular Neurobiology Citation Mol Neurobiol. 2021 Feb 10. Abstract Neurons are highly compartmentalized cells that depend on local protein synthesis. Messenger RNAs (mRNAs) have thus been detected in neuronal dendrites, and more

Authors Perego E, Köster S Journal Lab on a Chip Citation Lab Chip. 2021 Jan 25. Abstract Despite the importance for cellular processes, the dynamics of molecular assembly, especially on fast time scales, is not yet fully understood. To this end, we present a multi-layer microfluidic device and combine it

Authors Wittmeier A, Cassini C, Töpperwien M, Denz M, Hagemann J, Osterhoff M, Salditt T, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Rad (2021) 28. Abstract X-rays are emerging as a complementary probe to visible-light photons and electrons for imaging biological cells. By exploiting their small wavelength

Authors Kraxner J, Lorenz C, Menzel J, Parfentev I, Silbern I, Denz M, Urlaub H, Schwappach B, Köster S Journal Nanoscale Citation Nanoscale. 2020 Dec 22. Abstract The mechanical properties of biological cells are determined by the cytoskeleton, a composite biopolymer network consisting of microtubules, actin filaments and intermediate filaments