Increased autonomous bioluminescence emission from mammalian cells by enhanced cofactor synthesis
Authors Brinker T, Gregor C Journal Chemosensors Citation Chemosensors 2024, 12, 223. Abstract The bacterial bioluminescence system has been successfully implemented in mammalian cell lines, enabling the substrate-free luminescence imaging of living cells. One of the major limitations of the system is its comparatively low brightness. To improve light emission,