2022

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Left: Concept drawing of combination of optical cochlear implant (oCI) with gene therapy product (top), close-up of waveguide-based oCI prototype for excitation with red light (bottom). Middle: Top view of the cochlea. Optical excitation of the neurons allows specific areas of the cochlea to be targeted for excitation. Right: Cross-section through the cochlea. Source: Keppeler/Moser (UMG)

12.08.2022

State of Lower Saxony promotes the preclinical development of the optical cochlear implant

The state of Lower Saxony and the Volkswagen Foundation approve funding for scientists at the UMG and the MBExC Cluster of Excellence of about 1 milion euros of the “SPRUNG” (formerly: “Niedersächsisches Vorab”). The team around Tobias Moser focuses on the development of the optical cochlear implant for the restoration
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Left: Concept drawing of combination of optical cochlear implant (oCI) with gene therapy product (top), close-up of waveguide-based oCI prototype for excitation with red light (bottom). Middle: Top view of the cochlea. Optical excitation of the neurons allows specific areas of the cochlea to be targeted for excitation. Right: Cross-section through the cochlea. Source: Keppeler/Moser (UMG)

12.08.2022

State of Lower Saxony promotes the preclinical development of the optical cochlear implant

The state of Lower Saxony and the Volkswagen Foundation approve funding for scientists of the UMG and the MBExC Cluster of Excellence of about 1 milion euros of the “SPRUNG” (formerly: “Niedersächsisches Vorab”) for the development of the optical cochlear implant for the restoration of hearing in humans. (umg/mbexc) Hearing
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09.08.2022

IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter

Authors Katsenelson M, Shapira I, Abbas E, Jevdokimenko K, Styr B, Ruggiero A, Aïd S, Fornasiero EF, Holzenberger M, Rizzoli SO, Slutsky I Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2121040119. Abstract Regulation
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07.08.2022

Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices

Authors Veress B, Peruzzi N, Eckermann M, Frohn J, Salditt T, Bech M, Ohlsson B Journal World Journal of Gastroenterology Citation World J Gastroenterol. Aug 7, 2022; 28(29): 3994-4006. Abstract Background: The enteric nervous system (ENS) is situated along the entire gastrointestinal tract and is divided into myenteric and submucosal
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03.08.2022

From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms

Authors Shvachiy L, Amaro-Leal Â, Outeiro TF, Rocha I, Geraldes V Journal Biology Citation Biology (Basel). 2022 Aug 3;11(8):1164. Abstract Lead is a heavy metal whose widespread use has resulted in environmental contamination and significant health problems, particularly if the exposure occurs during developmental stages. It is a cumulative toxicant
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02.08.2022

Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice

Authors Dullin C, Svetlove A, Zschüntzsch J, Alves F Journal Scientific Reports Citation Sci Rep. 2022 Aug 2;12(1):13299. Abstract Retrospective gating (RG) is a well established technique in preclinical computed tomography (CT) to assess 3D morphology of the lung. In RG additional angular projections are recorded typically by performing multiple
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28.07.2022

Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study

Authors Lange T, Backhaus SJ, Beuthner BE, Topci R, Rigorth KR, Kowallick JT, Evertz R, Schnelle M, Ravassa S, Díez J, Toischer K, Seidler T, Puls M, Hasenfuß G, Schuster A Journal Journal of Cardiovascular Magnetic Resonance Citation J Cardiovasc Magn Reson. 2022 Jul 28;24(1):45. Abstract Background: Since cardiovascular magnetic
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27.07.2022

Stefan Hell elected to the Order Pour le mérite

The association honors the Nobel laureate in chemistry, director of the Max Planck Institute (MPI) for Multidisciplinary Natural Sciences in Göttingen and MBExC member for his special services to science. Admission to the Order is one of the highest honors that can be bestowed on researchers or artists in Germany.
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27.07.2022

Stefan Hell elected to the Order Pour le mérite

The association honors the Nobel laureate in chemistry and director of the Max Planck Institute (MPI) for Multidisciplinary Natural Sciences in Göttingen for his special services to science. Admission to the Order is one of the highest honors that can be bestowed on researchers or artists in Germany. In addition
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23.07.2022

GGPS1-associated muscular dystrophy with and without hearing loss

Authors Kaiyrzhanov R, Perry L, Rocca C, Zaki MS, Hosny H, Araujo Martins Moreno C, Phadke R, Zaharieva I, Camelo Gontijo C, Beetz C, Pini V, Movahedinia M, Zanoteli E, DiTroia S, Vuillaumier-Barrot S, Isapof A, Mehrjardi MYV, Ghasemi N, Sarkozy A, Muntoni F, Whalen S, Vona B, Houlden H,
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