2022

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10.05.2022

Science back in Touch with Society – face-to-face Summer Events 2022

This summer, the MBExC will again be present at several public events to engage and inspire people about its pioneering heart and brain research.   June , 10-12, 2022: Tag der Niedersachsen (Hannover) The MBExC will present several exhibits to to present its fascinating multiscale heart & brain research and
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05.05.2022

Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice

Authors Bali B, Gruber-Dujardin E, Kusch K, Rankovic V, Moser T Journal Life Science Alliance Citation Life Sci Alliance. 2022 May 5;5(8):e202101338 Abstract AAV-mediated optogenetic neural stimulation has become a clinical approach for restoring function in sensory disorders and feasibility for hearing restoration has been indicated in rodents. Nonetheless, long-term
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03.05.2022

α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

Authors Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, Kügler S Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2022 May 3;15:868790. Abstract α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson’s disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are
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The figure shows a cell with excessive alpha-synuclein (left) compared to a cell, where alpha-synuclein was genetically switched off (right). The cell nucleus is colored blue, the protein alpha-synuclein yellow.© Felipe Opazo / UMG

02.05.2022

Possible biomarker for Parkinson’s discovered using new MRI method

Certain metabolic products are suitable as indication for Parkinson’s disease. Researchers and MBExC members at the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the German Center for Neurodegenerative Diseases (DZNE) have used this insight in a first step to develop a new diagnostics
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02.05.2022

HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation

Authors Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, Łyszkiewicz M, Ziȩtara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C Journal Journal of Clinical Investigation Citation J Clin Invest. 2022 May 2;132(9):e153153. Abstract The relevance
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02.05.2022

Cellular and mitochondrial mechanisms of atrial fibrillation

Authors Jung P, Seibertz F, Fakuade FE, Ignatyeva N, Sampathkumar S, Ritter M, Li H, Mason FE, Ebert A, Voigt N. Journal Basic Research in Cardiology Citation Basic Res Cardiol. 2022 May 2;117(1):5. Abstract Dilated cardiomyopathy (DCM) is a major risk factor for heart failure and is associated with the
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Prof. Dr. Claus Ropers / Foto: spförtner

27.04.2022

ERC Advanced Grant for MBExC member Claus Ropers

MBExC member Claus Ropers, professor at the Physics department at Göttingen University and director of the Department of Ultrafast Dynamics at the Max Planck Institute for Multidisciplinary Sciences, receives the prestigious Advanced Grant from the European Commission for his innovative research project. With the ERC funding, Ropers’ team wants to
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Prof. Dr. med. Tobias Moser, Director of the Institute for Auditory Neuroscience Göttingen, UMG. Photo: MBExC / spförtner

26.04.2022

European funding for excellent research on hearing

Auditory neuroscientist of the University Medical Center Göttingen receives Advanced Grant of the European Research Council for the second time. Tobias Moser, MD, Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen (UMG) was awarded an Advanced Grant of the European Research Council (ERC). The ERC
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Prof. Dr. med. Tobias Moser, Director of the Institute for Auditory Neuroscience Göttingen, UMG. Photo: MBExC / spförtner

26.04.2022

European funding for excellent research on hearing

MBExC speaker Tobias Moser, director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen, received an ERC Advanced Grant. The European Research Council (ERC) supports his research project „Solving the dynamic range problem of hearing: deciphering and harnessing cochlear mechanisms of sound intensity coding (DynaHear)“ over five
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25.04.2022

Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes

Authors Chegão A, Guarda M, Alexandre BM, Shvachiy L, Temido-Ferreira M, Marques-Morgado I, Fernandes Gomes B, Matthiesen R, Lopes LV, Florindo PR, Gomes RA, Gomes-Alves P, Coelho JE, Outeiro TF, Vicente Miranda H Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2022 Apr 25;8(1):51. Abstract Alpha-synuclein (aSyn) is a central
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