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3D-MINFLUX data of the protein bassoon in the synapses of rod photoreceptors prepared using Heat Assisted Rapid Dehydration (HARD). (Source: abberior Instruments)

15.07.2022

Molecular map of the synapse

Scientists at the Institute for Auditory Neuroscience, UMG, the Max Planck Institute for Multidisciplinary Sciences and the abberior Instruments GmbH apply high-resolution 3D-MINFLUX technology for precise 3D representation of the molecular organization in the active zone of rod photoreceptor cells. Published in Science Advances. Link to the press release of
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14.07.2022

Is there an unmet medical need for improved hearing restoration?

Authors Wolf BJ, Kusch K, Hunniford V, Vona B, Kühler R, Keppeler D, Strenzke N, Moser T Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2022 Jul 14:e15798. Abstract Hearing impairment, the most prevalent sensory deficit, affects more than 466 million people worldwide (WHO). We presently lack causative treatment for
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13.07.2022

Structure of a backtracked hexasomal intermediate of nucleosome transcription

Authors Farnung L, Ochmann M, Garg G, Vos SM, Cramer P Journal Molecular Cell Citation Mol Cell. 2022 Jul 13:S1097-2765(22)00610-4. Abstract During gene transcription, RNA polymerase II (RNA Pol II) passes nucleosomes with the help of various elongation factors. Here, we show that RNA Pol II achieves efficient nucleosome passage
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13.07.2022

A Sequential Two-Step Priming Scheme Reproduces Diversity in Synaptic Strength and Short-Term Plasticity

Authors Lin KH, Taschenberger H, Neher E Journal Proceedings of the National Academy of Sciences Citation Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2207987119. Abstract Glutamatergic synapses display variable strength and diverse short-term plasticity (STP), even for a given type of connection. Using nonnegative tensor factorization and conventional
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Impressions from the Night of Science, Göttingen 2022, photos: MBExC/SFB889, UMG

12.07.2022

MBExC at the Night of Science 2022

With a lecture by MBExC spokesperson Tobias Moser, further scientific lectures and a booth within the Sensory Trail, organized by the Collaborative Research Center 889, the Cluster of Excellence MBExC presented itself to many interested visitors at the 5th Night of Science in Göttingen in the Central Lecture Hall Building
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Marina Eckermann receives the Academic Award of the Universitätsbund Göttingen e.V. for her doctoral thesis. Photo: MBExC

11.07.2022

Marina Eckermann receives Academic Award of the Universitätsbund Göttingen e.V.

Dr. Marina Eckermann, former Hertha Sponer Collegian, receives the Academic Award of the Universitätsbund Göttingen e.V. for her doctoral thesis at the Göttingen University. For her dissertation, the physicist combined high-resolution three-dimensional X-ray imaging with modern mathematical and statistical analysis methods to identify changes in nerve tissue as a result
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11.07.2022

Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function

Authors Lin SJ, Vona B, Porter HM, Izadi M, Huang K, Lacassie Y, Rosenfeld JA, Khan S, Petree C, Ali TA, Muhammad N, Khan SA, Muhammad N, Liu P, Haymon ML, Rüschendorf F, Kong IK, Schnapp L, Shur N, Chorich L, Layman L, Haaf T, Pourkarimi E, Kim HG, Varshney
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07.07.2022

Whole genome sequencing for newborns—The devil is in the details

Authors Vona B Journal Clinicial and Translational Discovery Citation Clin Transl Dis. 2022 Jul 7. Abstract No abtract available. DOI 10.1002/ctd2.102  
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MBExC at the IdeenExpo 2022. Foto: MBExC

06.07.2022

MBExC at the IdeenExpo 2022

The MBExC currently presents selected research exhibits at the IdeenExpo in Hannover, which runs from 02 -10 July 2022. The  nationwide, successful cooperation between business, science and politics aims to promote next generation careers. It combines sound knowledge transfer with a high fun factor, and invites young visitors and families
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Prof. Dr. Claus Ropers / Foto: spförtner

06.07.2022

Claus Ropers receives Diels Planck Medal

Solid state physicist and MBExC member Professor Claus Ropers from the Max Planck Institute for Multidisciplinary Sciences and the University of Göttingen receives the Diels Planck Medal of the Kiel Nano, Surface and Interface Science (KiNSIS). Ropers is being honoured for his experimental pioneering work in the field of ultrafast
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