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New gene therapy for children born deaf in clinical trials
01.02.2024

New gene therapy for children born deaf in clinical trials

To date, hearing impairment can only be treated with medical devices such as hearing aids or cochlear implants. Gene therapy could offer an alternative in certain cases in the future. Building on pioneering work by researchers at the University Medical Center Göttingen (UMG), children suffering from a hearing impairment due
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Energy supply in human cells is subject to quality control
19.01.2024

Energy supply in human cells is subject to quality control

Researchers at the University Medical Center Göttingen (UMG) and members of the MBExC have discovered a new quality control mechanism that regulates the energy production in human cells. This process takes place in mitochondria, the power plants of the cell. Malfunctions of mitochondria lead to serious diseases of the nerves,
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New insights into sound coding in our ears
14.12.2023

New insights into sound coding in our ears

Sensory cells and neurons in the ear communicate by secreting neurotransmitter in response to sound stimuli. Scientists of the University Medical Center Göttingen, the Cluster of Excellence Multiscale Bioimaging, and the Max Planck Institute for Multidisciplinary Sciences describe new details of this process that regulates the release of neurotransmitters and
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Detecting side effects of new drugs on the heart more efficiently
05.12.2023

Detecting side effects of new drugs on the heart more efficiently

Scientists at the University Medical Center and the University of Göttingen have developed a new approach to keep intact heart tissue for about two weeks in culture for more efficient cardiotoxicity screening of new active substances and therapeutic approaches. The advantage: this method is already effective in a very early
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Protein stock for the beginning of a new life
06.11.2023

Protein stock for the beginning of a new life

How mysterious structures in the egg cell supply the early embryo as protein storage sites When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs to
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Heart and Brain Together in Focus – Public lecture series starting Nov. 7, 2023
13.10.2023

Heart and Brain Together in Focus – Public lecture series starting Nov. 7, 2023

„Herz und Hirn gemeinsam im Fokus“ (Heart and Brain Together in Focus) is the title of the public lecture series of the University of Göttingen and the Lower Saxony Academy of Sciences and Humanities in Göttingen in the winter semester 2023/2024. In the series, scientists of the Göttingen Cluster of
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State of Lower Saxony supports further preclinical development of optical cochlear implants
29.06.2023

State of Lower Saxony supports further preclinical development of optical cochlear implants

The State of Lower Saxony and the VolkswagenFoundation have granted researchers of the University Medical Center Göttingen, the Leibniz University Hannover and the Clusters of Excellence Multiscale Bioimaging and Hearing4all funding by the zukunft.niedersachsen program. Their project on the development of optical cochlear implants for the restoration of hearing in
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Emilie Macé takes up new professorship for Dynamics of Excitable Cell Networks
03.04.2023

Emilie Macé takes up new professorship for Dynamics of Excitable Cell Networks

Neuroscientist and expert in functional ultrasound bioimaging strengthens research profile of the Cluster of Excellence MBExC.   (mbexc/umg) Prof. Dr. Emilie Macé has taken up the university professorship for Dynamics of Excitable Cell Networks at the University Medical Center Göttingen (UMG) on 1st April 2023. The professorship was newly established
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In the control room for hearing with light
03.03.2023

In the control room for hearing with light

Optical cochlear implants promise to improve the restoration of hearing in hearing loss and deafness. A Göttingen team of hearing researchers around Antoine Huet have now defined for the first time the biologically plausible range of stimulation parameters for the use of the optical cochlea implant in humans. Published in
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ERC Proof of Concept Grant for Tobias Moser
23.02.2023

ERC Proof of Concept Grant for Tobias Moser

Auditory neuroscientist of the University Medical Center Göttingen receives additional funding by the European Research Council. His project “OptoWave” concentrates on optimizing the optical cochlear implant for the application in hearing impaired people. (mbexc/umg) Tobias Moser, MD, Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen
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European funding for Rubén Fernández Busnadiego
31.01.2023

European funding for Rubén Fernández Busnadiego

Expert in cryo-electron microscopy at the University Medical Center Göttingen receives Consolidator Grant of the European Research Council to investigate the membrane architecture of nerve cells and its pathological alterations in axonopathies. (mbexc/umg) Prof. Dr. Rubén Fernández Busnadiego from the Institute for Neuropathology at the University Medical Center Göttingen (UMG)
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European top funding for investigating the exciting mechanisms of mitochondrial gene expression
05.10.2022

European top funding for investigating the exciting mechanisms of mitochondrial gene expression

Prof. Dr. Peter Rehling, cell biochemist at the University Medical Center Göttingen recives for the second time an Advanced Grant of the European Research Council (ERC). (umg/mbexc) Prof. Dr. Peter Rehling, Director of the Institute of Cellular Biochemistry at the University Medical Center Göttingen (UMG), spokesperson of the Göttingen Collaborative
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State of Lower Saxony promotes the preclinical development of the optical cochlear implant
12.08.2022

State of Lower Saxony promotes the preclinical development of the optical cochlear implant

The state of Lower Saxony and the Volkswagen Foundation approve funding for scientists of the UMG and the MBExC Cluster of Excellence of about 1 milion euros of the “SPRUNG” (formerly: “Niedersächsisches Vorab”) for the development of the optical cochlear implant for the restoration of hearing in humans. (umg/mbexc) Hearing
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Stefan Hell elected to the Order Pour le mérite
27.07.2022

Stefan Hell elected to the Order Pour le mérite

The association honors the Nobel laureate in chemistry and director of the Max Planck Institute (MPI) for Multidisciplinary Natural Sciences in Göttingen for his special services to science. Admission to the Order is one of the highest honors that can be bestowed on researchers or artists in Germany. In addition
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Unique technology platform at the MBExC Cluster of Excellence combines cellular electrophysiology and optogenetics
22.07.2022

Unique technology platform at the MBExC Cluster of Excellence combines cellular electrophysiology and optogenetics

New technology platform combines high-throughput recordings of cellular electrophysiology of isolated cardiomyocytes and neurons and their optical stimulation with light. Electrical activity is one of the most important common features of the heart and the brain. The goal of the Göttingen Cluster of Excellence “Multiscale Bioimaging: From Molecular Machines to
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Molecular map of the synapse
15.07.2022

Molecular map of the synapse

Scientists at the Institute for Auditory Neuroscience, UMG, the Max Planck Institute for Multidisciplinary Sciences and the abberior Instruments GmbH apply high-resolution 3D-MINFLUX technology for precise 3D representation of the molecular organization in the active zone of rod photoreceptor cells. Published in Science Advances. (umg/mbexc) For the processing of sensory
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The first light-controlled drug that could improve the hearing of people with cochlear implants
20.05.2022

The first light-controlled drug that could improve the hearing of people with cochlear implants

Researchers at the University Medical Center Göttingen and the Institute for Bioengineering of Catalonia (IBEC) in Spain achieve, for the first time, in vivo light-activated auditory stimulation without the need for genetic manipulation. This new light-controlled drug, capable of triggering the neural pathways involved in hearing, can contribute to improving
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How Junctophilins organize electrically excitable cells
11.05.2022

How Junctophilins organize electrically excitable cells

Experts from the University Medical Center Göttingen and the Baylor College of Medicine in Houston, Texas, summarize 20 years of Junctophilin research, new molecular analyses, and the role of Junctophilins in the development of human diseases in a comprehensive in-depth review article. Published with Spotlight Cover in the renowned journal
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