Events

Host: Jörg Enderlein (U GOE), MBExC
Local organizer: Alexander Egner (IFNANO)

Speaker: Thomas Burg, TU Darmstadt
Microsystems for cryo-CLEM

Abstract:
Correlative Light and Electron Microscopy (CLEM) is a powerful tool for investigating the connections between cellular structure and function. Performing CLEM on vitrified cells at cryogenic temperature (cryo-CLEM) is particularly interesting, as sub-cellular structures can be preserved very close to the native state and radiation damage is significantly reduced. However, cryo-CLEM technology still has several important limitations today. First, conventional cryofixation by high-pressure freezing or plunge freezing interrupts live-cell imaging, as it requires sample preparation and transfer between instruments. Second, only air objectives are available in cryogenic light microscopy, limiting the numerical aperture to less than one. To overcome the first limitation, our group has introduced a microsystems-based cryofixation technology that enables cryofixation of thin samples (< 20 µm) within fully operating microfluidic devices directly in the light microscope. Recently, we have been investigating applications of this approach to studies of cell biomechanics and cryopreservation. To address the second limitation, we designed a new type of light microscope and cryo-immersion objectives. I will describe recent advances towards integrating this technology into a new immersion-based correlative light and electron microscopy workflow and enabling cryo-STED microscopy with immersion objectives. We expect that, together, microfluidic cryofixation and immersion-based cryo-CLEM will be of particular interest for studying dynamic relationships between cell stimulation, function, and structure at the nanometer scale.   Please find here the PDF of the announcement:

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Dear Friends and Colleagues,

we are excited to host the 10th Cardiovascular Bioengineering (CVBE) Symposium from June 18th to 20th, 2026 in Göttingen at the German Primate Center. CVBE has established a legacy in bringing together global leaders in fundamental and translational research related to heart regeneration and repair.

Abstract submission remains open until June 1st.

From the submitted abstracts, we will select presenters for the Early Career Investigator Award session Friday the 19th, chaired by senior editors from Nat Med, Science and Lancet. In addition to our excellent faculty, we are proud that Nobel Prize laureates Erwin Neher (1991, Physiology or Medicine) and Stefan Hell (2014, Chemistry) will present exciting keynote lectures.

Please register here if you intend to present an abstract/poster.
Please register here if you intend to participate without an abstract/poster presentation.

For updates and registration information, please visit: https://dzhk.de/newsroom/events/cvbe-2026.

Here you find the PDF of the flyer: and the programm

Internal event: 14 July 2026, 5.p.m.

Welcoming of new collegians, information, flash talks, collegains speed dating, networking

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

MBExC Closing Symposium “Bioimaging Across Scales”

Date: Monday, 28th September 2026 and Tuesday, 29th September 2026

Location: Alte Mensa, Wilhelmsplatz, Göttingen

Organizer: MBExC