Research team including Göttingen University develops high-resolution fluorescence microscope
What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and Oxford, in collaboration with the University Medical Center Göttingen (UMG), have succeeded in developing a microscope with resolutions better than five nanometres (five billionths of a metre). This is roughly equivalent to the width of a hair split into 10,000 strands. Their new method was published in Nature Photonics.
The current process enables resolutions of around 10 to 20 nanometres. MBExC member Professor Jörg Enderlein’s research group at the University of Göttingen’s Faculty of Physics has now been able to double this resolution again – with the help of a highly sensitive detector and special data analysis. This means that even the tiniest details of protein organization in the connecting area between two nerve cells can be very precisely revealed.
Link to the press release article
