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february, 2025

202527feb1:00 PM2:00 PMMBExC LectureNovel concepts in cardioprotection and ischemic heart disease: from pathophysiology to treatment1:00 PM - 2:00 PM MPI-NAT, City Campus, Hermann-Rein-Str. 3Speaker:Gemma Vilahur, Ph.D, FESC, Hospital de la Santa Creu i Sant Pau, Barcelona

Event Details

Gemma Vilahur, Ph.D, FESC from the Research Institute Hospital de la Santa Creu i Sant Pau, Barcelona, Spain will held a talk about “Novel concepts in cardioprotection and ischemic heart disease: from pathophysiology to treatment” during the MBExC Lecture on 27 February, 2025 at 1:00 p.m.

Abstract
Ischemic heart disease remains the leading cause of morbidity and mortality globally, and the extent of myocardial infarction significantly influences the progression to heart failure. Currently, there is not therapeutic strategy available in the clinical setting able to limit infarct size. Consequently, extensive research has focused on identifying novel targets and developing innovative cardioprotective strategies to reduce cardiac damage and improve patient outcomes.
Recent advances in understanding the pathophysiological mechanisms behind myocardial infarction have led to new concepts in cardioprotection. Metabolic disturbances can heighten myocardial vulnerability during ischemic events and reduce the effectiveness of traditional treatments. A deeper exploration of how metabolic alterations impact cardioprotection has opened avenues for targeted interventions. Exploring the intricate relationship between comorbidities and cardiovascular health is crucial for crafting personalized cardioprotective strategies tailored to the patient’s needs.
Finally, beyond investigating new pharmacological targets, recent developments in therapeutic approaches—including pharmacological repositioning and lifestyle modifications—show promise for enhancing outcomes in patients with multiple health challenges. These strategies aim not only to boost cardioprotection but also to foster overall cardiovascular health, ultimately contributing to better long-term prognoses for individuals at risk of ischemic heart disease.


Host: Prof. Dr. Niels Voigt, University Medical Center Göttingen

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