small lecture hall at the MPI-NAT City Campus
Hermann-Rein-Str.3
behind the library
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Tim Salditt
Tobias Moser
Vladan Rankovic
Rubén Fernández-Busnadiego
Peter Rehling
Antonio Martinez-Sanchez
Han Chen
Hauke Hillen
Housen Li
Julia Preobraschenski
Jörg Wegener
Ricarda Richter-Dennerlein
Sarah Köster
Stefan Stoldt
Thomas Oertner
Tiago Outeiro
Event Tag
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Cell biology
Cryo-electron tomography
Cell biology
Cryo-electron tomography
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november
Event Details
Jung-Bum Shin, Ph.D. from the Department of Neuroscience, The University of Virginia School of Medicine, USA will give a talk about
Event Details
Jung-Bum Shin, Ph.D. from the Department of Neuroscience, The University of Virginia School of Medicine, USA will give a talk about “The Sensitivity of Auditory Sense and How We Maintain It” during the MBExC Lecture on November 9th, 2023 at 11:00 am at the small lecture hall (behind the library) at the Max Planck Institute for Multidisciplinary Sciences, Hermann-Rein-Str. 3.
Abstract:
Repair of the stereocilia actin core
Given that mammalian hair cells do not regenerate, the repair of hair cell damage is important for continued auditory function throughout life. One part of our research focuses on the repair of the F-actin-based stereocilia cores, which can be damaged by loud noise. Currently we are working to determine the mechanism by which the LIM domain protein XIRP2 is involved in stereocilia repair.
Myosin-VIIA (Myo7a) in tip link tension
Mutations in myosin-VIIa (MYO7A) cause Usher syndrome type 1, characterized by combined deafness and blindness. MYO7A is proposed to function as a motor that tensions the hair cell mechanotransduction (MET) complex, but conclusive evidence was lacking. Our studies reveal an unexpected isoform diversity of MYO7A expression in the cochlea and highlight MYO7A’s essential role in tensioning the hair cell MET complex. We are investigating the presence and functional relevance of other isoforms of MYO7A in hair cells. We are also interested in identifying the cis- and trans-factor that regulate the cell-type specific expression of the various MYO7A isoforms.
Host: Prof. Dr. Tina Pangršič, University Medical Center Göttingen
Organizer
MBExC
december
Event Details
The MBExC Research Alliance 1.2 will meet in the small lecture hall (behind the library) of the MPI-NAT City Campus. Agenda: Andre Fischer, Clinic of Psychiatry and Psychotherapy, UMG & German Center
Event Details
The MBExC Research Alliance 1.2 will meet in the small lecture hall (behind the library) of the MPI-NAT City Campus.
Agenda:
Andre Fischer, Clinic of Psychiatry and Psychotherapy, UMG & German Center for Neurodegenerative diseases (DZNE).
The unexplored therapeutic potential of non-coding RNAs in heart and brain diseases
Marina Rodnina, MPI-NAT, Department of Physical Biochemistry
Effects of mRNA epigenetic marks on translation: mechanisms and open questions
Bernd Wollnik, Institute of Human Genetics, University Medical Center Göttinge
Epigenetic dysregulation in neurodevelopmental syndromes: A medical genetic approach
Karl Toischer, Clinic for Cardiology and Pneumology, University Medicine Göttingen
(Epi)Transcriptomics and epigenetics in cardiac hypertrophy and heart failure
Moderator: André Fischer
Organizer
MBExC