The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chairs: Tobias Moser and Thomas Mager

Professor Adam E. Cohen from the Departments of Chemistry and Chemical Biology, and Physics, Harvard University and Howard Hughes Medical Institute in Cambridge will talk about “All-optical electrophysiology for probing neural circuit dynamics”. 

Abstract

Combined optogenetic perturbation and voltage imaging enables high-resolution mapping of bioelectrical dynamics in intact tissues. I will describe application of these tools to Layer 1 of the mouse barrel cortex. We developed techniques to distinguish the separate contributions of excitatory and inhibitory synaptic inputs to membrane potential. By combining patterned optogenetic stimulation, voltage imaging, and numerical simulations of neural dynamics we discovered surprising phase transitions in the dynamics of L1 interneurons which may affect how the brain regulates attention.

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de