Zimmermann, Wolfram-Hubertus

Authors Dittrich GM, Zimmermann WH. Journal Cell Stem Cell Citation Cell Stem Cell. 2026 Aug 6;33(8):1243-1245. Abstract Modeling of cardiac pathologies in tissue-engineered models is coming of age. Two independent studies by Reid et al.1 and Tani et al.2 present in-depth multi-phenomics data from a human cardiac organoid (hCO) model

Authors Plota D, Nosheen Saleem H, Lin KH, Wali R, Cheruiyot C, Münzel L, Hutschenreiter T, Tiburcy M, Meyer T, Habeck M, Wiedmann F, Schmidt C, Zimmermann WH, Ebert A Journal Journal of Translational Medicine Citation J Transl Med (2026). Abstract Background: Sodium–glucose cotransporter 2 inhibitors (SGLT2i) are now widely

Authors Sinha M, Yu B, Mendes da Silva R, Roelleke U, Luley P, Tiburcy M, Zimmermann WH, Burghammer M, Koester S Journal BioRxiv Citation bioRxiv 2026.06.04.730059 Abstract Imaging the structural organization inside cells in their native state is essential for understanding how the arrangement and interactions among molecular components give

Authors Zimmermann WH, Ensminger S, Kutschka I, Paitazoglou C, Seidler T, Brandenburg S, Anker SD, Bader N, Bergau L, Bremmer F, Diogo PG, Eitel I, Fujita B, Gerecke B, Hasenfuß G, Hellenkamp K, Hermann-Lingen C, Jebran AF, Jurczyk D, Knaus R, Legler T, Lotz J, Placzek M, Pühler T, Riggert

Authors Haertter D, Hauke L, Driehorst T, Nish Ki, Zimmermann W, Schmidt CF Journal eLife Citation eLife13:RP97321. Abstract Cardiac contraction is driven by the collective action of cardiomyocytes, that contain parallel bundles of myofibrils consisting of linear chains of sarcomeres, the basic force-generating units. The dynamics of individual sarcomeres within

Authors Fell J, Pavez-Giani M, Koitka F, Kensah G, Santos GL, van der Vorst EPC, Lenz C, Salinas G, Busley AV, Fedorenko A, Hindmarsh R, Wolf CM, Lutz S, Hasenfuss G, Zimmermann WH, Wollnik B, Cyganek L Journal Circulation Citation Circulation. 2026 Apr 16. Abstract Background: Genetic variants in components

Authors Streckfuss-Bömeke K, Zelarayán LC, Schnabel RB, Kränkel N, Maack C, Eschenhagen T, Kappler HE, Klingmüller U, Kramann R, Loewe A, Milting H, Molina CE, Panáková D, Podesser BK, Schnieke A, Schröder K, Seidel T, Sossalla S, Zgierski-Johnston C, Zimmermann WH, Rog-Zielinska EA, Kohl P Journal Physiological Reports Citation Physiol

Authors Hofhuis J, Tiburcy M, Hartmann Y, Bersch K, Wagdi A, Gutiérrez-Gutiérrez O, Solano R, Thiele L, Walper M, Göbel M, Hübner W, Berecic B, Casini M, Tirilomis P, Unger A, Lipstein N, Sossalla S, Huser T, Streckfuss-Bömeke K, Elkenani M, Toischer K, Kohlhaas M, Dudek J, Zimmermann WH, Voigt

Authors Haertter D, Hauke L, Driehorst T, Nishi K, Long J, Tiburcy M, Berecic B, Primeßnig A, Bao G, Cyganek L, Schmidt CF, Zimmermann WH Journal BioRxiv Citation bioRxiv 2025.04.29.650605. Abstract Cardiomyocyte function critically depends on sarcomere dynamics and their organization in myofibrils. To uncover how cardiomyocyte function emerges from

Authors Tiper Y, Xie Z, Hofemeier AD, Lad H, Luber M, Krawetz R, Betz T, Zimmermann WH, Morton AB, Segal SS, Gilbert PM. Journal American Journal of Physiology. Cell Physiology Citation Am J Physiol Cell Physiol. 2025 Feb 28. Abstract Skeletal muscle microtissues are engineered to develop therapies for restoring