Richter-Dennerlein, Ricarda

Authors Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P Journal Cell Citation Cell 2021 Oct 20. Abstract The human mitochondrial genome encodes thirteen core subunits of the oxidative phosphorylation system, and defects

Authors Lavdovskaia E, Hillen HS, Richter-Dennerlein R Journal Trends in Cell Biology Citation Trends Cell Biol. 2021. Abstract Final maturation steps during ribo-some biogenesis require the assis-tance of assembly and qualitycontrol factors to ensure the foldingof rRNA and proteins into a func-tional translation machinery. Herewe integrate several recent struc-tural snapshots

Authors Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E, Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein R Journal Nature Communications Citation Nat Commun. 2021 Jun 16;12(1):3672. Abstract Ribosome biogenesis requires auxiliary factors to promote folding and assembly of ribosomal proteins and RNA. Particularly, maturation of the peptidyl transferase center (PTC)

Authors Maiti P, Lavdovskaia E, Barrientos A, Richter-Dennerlein R Journal Trends in Cell Biology Citation Trends Cell Biol. 2021 Jan 5:S0962-8924(20)30254-3. Abstract Mitoribosomes catalyze essential protein synthesis within mitochondria. Mitoribosome biogenesis is assisted by an increasing number of assembly factors, among which guanosine triphosphate hydrolases (GTPases) are the most abundant

Authors Lavdovskaia E, Denks K, Nadler F, Steube E, Linden A, Urlaub H, Rodnina MV, Richter-Dennerlein R Journal Nucleic Acids Research Citation Nucleic Acids Res. 2020 Dec 2;gkaa1132. Abstract Translation and ribosome biogenesis in mitochondria require auxiliary factors that ensure rapid and accurate synthesis of mitochondrial proteins. Defects in translation

Authors Wang C, Richter-Dennerlein R, Pacheu-Grau D, Liu F, Zhu Y, Dennerlein S, Rehling P Journal EMBO Reports Citation EMBO Rep. 2020 Jan 7;21(1):e48833. Abstract The mitochondrial genome encodes for thirteen core subunits of the oxidative phosphorylation system. These proteins assemble with imported proteins in a modular manner into stoichiometric