Huisken, Jan

Authors Müller GF, Göpel T, Scherf N, Huisken J. Journal Frontiers in Bioinformatics Citation Front Bioinform. 2026 Mar 10;6:1757489. Abstract Variation is a foundational biological principle that has historically been marginalized-both due to limited experimental accessibility and because of idealized, stereotypic blueprints rooted in essentialist thinking. With the advent of

Authors Roos L, Meric Diniz A, Koert E, Schilling M, Uhl M, Thirumalai A, Aakhte M, Kusch K, Huisken J, Moser T, Pape C Journal BioRxiv Citation bioRxiv 2025.11.16.688700. Abstract With the emergence of gene and optogenetic therapies targeting deafness, the comprehensive analysis of the molecular anatomy and physiology of

Authors Aakhte M, Müller GF, Roos L, Li J, Göpel T, Weiss KR, Diniz AM, Wenzel J, Schwaninger M, Moser T, Huisken J Journal Nature Biotechnology Citation Nat Biotechnol. 2025 Nov 13. Abstract Light-sheet microscopy is ideal for imaging large and cleared tissues, but achieving a high isotropic resolution for

Authors Liu Y, Mueller GF, Kowitz L, Chobola T, Weiss K, Maier P, Luo J, Roessing M, Stenzel M, Grueneboom A, Paetzold J, Erturk A, Navab N, Marr C, Chen J, Huisken J, Peng T Journal BioRxiv Citation bioRxiv 2025.10.26.684661. Abstract Selective plane illumination microscopy (SPIM, also known as light

Authors Zgierski-Johnston CM, Huisken J Journal The Journal of Physiology Citation J Physiol. 2025 Aug 22 Abstract No abstract available. DOI 10.1113/JP289664   Pubmed Link  

Authors Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F Journal Nature Communications Citation Nat Commun. 2024 Aug 31;15(1):7589. Abstract The contribution of endocardial cells (EdCs) to the

Authors Milosevic N, Müller G, Huisken J, Scherf N Journal Arxiv Citation arXiv:2406.03845. Abstract In this work, we introduce the concept of Active Representation Learning, a novel class of problems that intertwines exploration and representation learning within partially observable environments. We extend ideas from Active Simultaneous Localization and Mapping (active

Authors Gritti N, Power RM, Graves A, Huisken J Journal Nature Methods Citation Nat Methods (2024). Abstract Time-lapse fluorescence microscopy is key to unraveling biological development and function; however, living systems, by their nature, permit only limited interrogation and contain untapped information that can only be captured by more invasive