Grubmüller, Helmut

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28.02.2022

Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel

Authors Kolar MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H Journal Nucleic Acids Research Citation Nucleic Acids Res. 2022 Feb 28;50(4):2258-2269. Abstract The ribosome is a fundamental biomolecular complex that synthesizes proteins in cells. Nascent proteins emerge from the ribosome through a tunnel, where they may interact
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22.07.2021

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

Authors Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmüller H, Mankin AS, Innis CA, Vázquez-Laslop N, Wilson DN Journal Nature Communications Citation Nat Commun 12, 4466 (2021). Abstract Macrolides and ketolides comprise a family of clinically important antibiotics that
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28.10.2019

Sharing Data from Molecular Simulations

Authors Abraham M, Apostolov R, Barnoud J, Bauer P, Blau C, Bonvin A, Chavent M, Chodera J, Condic-Jurkic K, Delemotte L, Grubmuller H, Howard RJ, Jordan EJ, Lindahl E, Ollila OHS, Selent J, Smith DGA, Stansfeld PJ, Tiemann JKS, Trellet M, Woods C, Zhmurov A Journal Journal of Chemical Information
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