Göpfert, Martin

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30.03.2026

FRMPD4, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss

Authors Liedtke D, Rak K, Schrode KM, Hehlert P, Chamanrou N, Bengl D, Katana R, Heydaran S, Doll J, Han M, Nanda I, Senthilan PR, Jürgens L, Bieniussa L, Voelker J, Neuner C, Hofrichter MAH, Schröder J, Schellens RTW, de Vrieze E, van Wijk E, Zechner U, Herms S, Hoffmann
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17.03.2026

Myosin II-driven contractions of supporting cap cells promote sensory adaptation of Drosophila proprioceptors

Authors Guan C, Nishi K, Kreis CT, Bäumchen O, Göpfert MC, Schmidt CF Journal Current Biology Citation Curr Biol. 2026 Mar 17:S0960-9822(26)00223-X. Abstract Mechanoreceptors can be motile and actively amplify their mechanical input.1,2,3,4 We here found that the responses of mechanoreceptor cells can also be shaped actively by contractile supporting
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15.04.2025

Synchronization in epithelial tissue morphogenesis

Authors Richa P, Häring M, Wang Q, Choudhury AR, Göpfert MC, Wolf F, Großhans J, Kong D Journal Current Biology Citation Curr Biol. 2025 Apr 11:S0960-9822(25)00382-3. Abstract Coordination of cell behavior is central to morphogenesis, when arrays of cells simultaneously undergo shape changes or dynamic rearrangements. In epithelia, cell shape
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06.01.2025

NOMPC ion channel hinge forms a gating-spring that initiates mechanosensation

Authors Hehlert P, Effertz T, Gu RX, Nadrowski B, Geurten BRH, Beutner D, de Groot BL, Göpfert MC Journal Nature Neuroscience Citation Nat Neurosci. 2025 Jan 6. Abstract The sensation of mechanical stimuli is initiated by elastic gating springs that pull open mechanosensory transduction channels. Searches for gating springs have
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10.02.2022

Rethinking opsins

Authors Feuda R, Menon AK, Göpfert MC Journal Molecular Biology and Evolution Citation Mol Biol Evol. 2022 Feb 10:msac033. Abstract Opsins, the protein moieties of animal visual photo-pigments, have emerged as moonlighting proteins with diverse, light-dependent and -independent physiological functions. This raises the need to revise some basic assumptions concerning
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27.11.2020

Drosophila Mechanosensory Transduction

Authors Hehlert P, Zhang W, Göpfert MC Journal Trends in Neurosciences Citation Trends Neurosci. 2020 Nov 27:S0166-2236(20)30251-4. Abstract Mechanosensation in Drosophila relies on sensory neurons transducing mechanical stimuli into ionic currents. The molecular mechanisms of this transduction are in the process of being revealed. Transduction relies on mechanogated ion channels
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