Fischer, André

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04.01.2022

Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes

Authors Michurina A, Sakib S, Kerimoglu C, Krüger DM, Kaurani L, Islam R, Joshi PD, Schröder S, Centeno TP, Zhou J, Pradhan R, Cha J, Xu X, Eichele G, Zeisberg EM, Kranz A, Stewart FA, Fischer A Journal EMBO Journal Citation EMBO J. 2022 Jan 4; 41(1): e106459. Abstract In
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11.11.2021

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

Authors Kettwig M, Ternka K, Wendland K, Krüger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schröder S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer
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11.10.2021

A microRNA signature that correlates with cognition and is a target against cognitive decline

Authors Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimolgu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka
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08.10.2021

Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501

Authors Goldberg M, Islam MR, Kerimoglu C, Lancelin C, Gisa V, Burkhardt S, Krüger DM, Marquardt T, Malchow B, Schmitt A, Falkai P, Sananbenesi F, Fischer A Journal Translational Psychiatry Citation Transl Psychiatry. 2021 Oct 8;11(1):514. Abstract MicroRNAs have been linked to synaptic plasticity and memory function and are emerging
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17.09.2021

H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion

Authors Kerimoglu C, Pham L, Tonchev AB, Sakib MS, Xie Y, Sokpor G, Ulmke PA, Kaurani L, Abbas E, Nguyen H, Rosenbusch J, Michurina A, Capece V, Angelova M, Maricic N, Brand-Saberi B, Esgleas M, Albert M, Minkov R, Kovachev E, Teichmann U, Seong RH, Huttner WB, Nguyen HP, Stoykova
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27.08.2021

Cellular Prion Protein Mediates α-Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo

Authors Thom T, Schmitz M, Fischer AL, Correia A, Correia S, Llorens F, Pique AV, Möbius W, Domingues R, Zafar S, Stoops E, Silva CJ, Fischer A, Outeiro TF, Zerr I Journal Movement Disorders Citation Mov Disord. 2021 Aug 27. Abstract Background The cellular prion protein (PrPC) is a membrane-bound,
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15.07.2021

Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain

Authors Abbas E, Hassan MA, Sokpor G, Kiszka K, Pham L, Kerimoglu C,  Fischer A, Nguyen HP, Staiger JF, Tuoc  T Journal Frontiers in Cell and Developmental Biology Citation Front Cell Dev Biol. 2021 Jul 15;9:619538. Abstract Oligodendrocytes are responsible for axon myelination in the brain and spinal cord. Generation
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16.06.2021

Loss of BAF complex in developing cortex perturbs radial neuronal migration in a WNT signaling-dependent manner

Authors Sokpor G, Kerimoglu C, Nguyen H, Pham L, Rosenbusch J, Wagener R, Nguyen HP, Fischer A, Staiger JF, Tuoc T Journal Frontiers in Molecular Neuroscience Citation Front. Mol. Neurosci., 16 June 2021, 14: 687581. Abstract Radial neuronal migration is a key neurodevelopmental event indispensable for proper cortical laminar organization.
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23.03.2021

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex

Authors Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T Journal Stem Cell Reports Citation Stem Cell Reports. 2021 Mar 23:S2213-6711(21)00138-7. Abstract Intermediate progenitor cells (IPCs) are neocortical neuronal
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10.02.2021

The Coding And Small-Non-Coding Hippocampal Synaptic RNAome

Authors Epple R, Krüger D, Berulava T, Brehm G, Ninov M, Islam R, Köster S, Fischer A Journal Molecular Neurobiology Citation Mol Neurobiol. 2021 Feb 10. Abstract Neurons are highly compartmentalized cells that depend on local protein synthesis. Messenger RNAs (mRNAs) have thus been detected in neuronal dendrites, and more
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