Fernandez-Busnadiego, Ruben

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10.08.2020

Reliable estimation of membrane curvature for cryo-electron tomography

Authors Salfer M, Collado JF, Baumeister W, Fernández-Busnadiego R, Martínez-Sánchez A Journal PLoS Computational Biology Citation PLoS Comput Biol. 2020 Aug 10;16(8):e1007962. Online ahead of print. Abstract Curvature is a fundamental morphological descriptor of cellular membranes. Cryo-electron tomography (cryo-ET) is particularly well-suited to visualize and analyze membrane morphology in a
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07.02.2020

Stress- And Ubiquitylation-Dependent Phase Separation Of The Proteasome

Authors Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, Arai N, Ohtake F, Murata S, Inada T, Baumeister W, Fernandez-Busnadiego R, Tanaka K, Saeki Y Journal Nature Citation Nature. 2020 Feb;578(7794):296-300. Abstract The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation
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18.11.2019

Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity

Authors Collado J, Kalemanov M, Campelo F, Bourgoint C, Thomas F, Loewith R, Martinez-Sanchez A, Baumeister W, Stefan CJ, Fernandez-Busnadiego R Journal Developmental Cell Citation Developmental Cell 51, 476–487, November 18, 2019. Abstract Membrane contact sites (MCS) between the endoplasmic reticulum (ER) and the plasma membrane (PM) play fundamental roles
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07.10.2019

Dynamic instability of clathrin assembly provides proofreading control for endocytosis

Authors Chen Y, Yong J, Martinez-Sanchez A, Yang Y, Wu Y, De Camilli P, Fernandez-Busnadiego R, Wu M Journal Journal of Cell Biology Citation J Cell Biol. 2019 Oct 7;218(10):3200-3211. Abstract Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake of those
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